Evidence map›Paper›PMID 26255937›Full record

ReviewMutation research2015

Photosensitive human syndromes.

Graciela Spivak, Philip C Hanawalt

Open access · greenAbstract readReview
In one paragraph

Review in Mutation research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Xeroderma Pigmentosum: A Model for Human Premature Aging.The Journal of investigative dermatology · 2021
    Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Transcription-coupled repair: an update.Archives of toxicology · 2016
    Review
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Graciela SpivakDepartment of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: gspivak@stanford.edu.
Philip C HanawaltDepartment of Biology, Stanford University, Stanford, CA 94305, USA.
Stanford University · US

Funding

Role of transcription in genomic stabilityR01CA077712 · NCI · STANFORD UNIVERSITY · PI HANAWALT, PHILIP COURTLAND · 1998 to 2016
$5.6M
Oxidative DNA damage processing; role in human pathology and agingR01ES018834 · NIEHS · STANFORD UNIVERSITY · PI HANAWALT, PHILIP COURTLAND · 2010 to 2014
$1.7M
NCI NIH HHS R01 CA077712NIEHS NIH HHS ES018834NIEHS NIH HHS R01 ES018834
6 · The paper itself

Abstract

Photosensitivity in humans can result from defects in repair of light-induced DNA lesions, from photoactivation of chemicals (including certain medications) with sunlight to produce toxic mediators, and by immune reactions to sunlight exposures. Deficiencies in DNA repair and the processing of damaged DNA during replication and transcription may result in mutations and genomic instability. We will review current understanding of photosensitivity to short wavelength ultraviolet light (UV) due to genetic defects in particular DNA repair pathways; deficiencies in some are characterized by an extremely high incidence of cancer in sun-exposed tissues, while in others no cancers have been reported.

Indexed as

DNA BreaksDNA RepairGenomic InstabilityMutationPhotosensitivity DisordersHumansNeoplasms, Radiation-InducedSyndromeUltraviolet RaysDNA repairGlobal genomic repairPhotosensitivitySkin cancerTranscription-coupled repair

Identifiers

PMID26255937
PMCPMC4531261
OpenAlexW2087702780

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.