Evidence map›Paper›PMID 26255889›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2015

Viruses and Gram-negative bacilli dominate the etiology of community-acquired pneumonia in Indonesia, a cohort study.

Helmia Farida, M Hussein Gasem, Agus Suryanto, Monique Keuter, Nasirun Zulkarnain, Bambang Satoto, Annemiek A van der Eijk, R Djokomoeljanto, Hendro Wahyono, Henri A Verbrugh and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017
    Pooled it
  2. Global Antimicrobial Non-Susceptibility Patterns ofInfection and drug resistance · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Clinical Characteristics and Microorganisms Isolated in Community-Acquired Pneumonia in the COVID-19 Period.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Article
  7. Identification ofThe Journal of international medical research · 2022
    Article
  8. High frequency of Chlamydia pneumoniae and risk factors in children with acute respiratory infection.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  9. Hypervirulent Klebsiella pneumoniae.Clinical microbiology reviews · 2019
    Review
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Community-Acquired Pneumonia in the Asia-Pacific Region.Seminars in respiratory and critical care medicine · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Helmia FaridaDepartment of Medical Microbiology, Faculty of Medicine Diponegoro University - Dr. Kariadi Hospital, Semarang, Indonesia. Electronic address: helmia_farida@yahoo.com.
M Hussein GasemDepartment of Internal Medicine, Dr. Kariadi Hospital - Faculty of Medicine Diponegoro University, Semarang, Indonesia.
Agus SuryantoDepartment of Internal Medicine, Dr. Kariadi Hospital - Faculty of Medicine Diponegoro University, Semarang, Indonesia.
Monique KeuterDepartment of General Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.
Nasirun ZulkarnainDepartment of Radiology, Dr. Kariadi Hospital - Faculty of Medicine Diponegoro University, Semarang, Indonesia.
Bambang SatotoDepartment of Radiology, Dr. Kariadi Hospital - Faculty of Medicine Diponegoro University, Semarang, Indonesia.
Annemiek A van der EijkDepartment of Viroscience, Erasmus University Medical Centre, Rotterdam, The Netherlands.
R DjokomoeljantoDepartment of Internal Medicine, Dr. Kariadi Hospital - Faculty of Medicine Diponegoro University, Semarang, Indonesia.
Hendro WahyonoDepartment of Medical Microbiology, Faculty of Medicine Diponegoro University - Dr. Kariadi Hospital, Semarang, Indonesia.
Henri A VerbrughDepartment of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Juliëtte A SeverinDepartment of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands.
Peterhans J van den BroekDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Dr. Kariadi Hospital · IDErasmus MC · NLDiponegoro University · IDErasmus University Rotterdam · NLLeiden University Medical Center · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveKnowledge about the etiology of community-acquired pneumonia (CAP) is essential for adequate management. Presently, few studies about CAP are available from Southeast Asia. This study aimed to investigate the etiology, severity, and outcome of CAP in the most populous Southeast Asia country, Indonesia.

methodsFrom October 2007 to April 2009, adult patients admitted with CAP to two hospitals in Semarang, Indonesia, were included to detect the etiology of CAP using a full range of diagnostic methods. The severity of disease was classified according to the Pneumonia Severity Index (PSI). The outcome was assessed as 30-day mortality.

resultsIn total, 148 consecutive patients with CAP were included. Influenza virus (18%), Klebsiella pneumoniae (14%), and Streptococcus pneumoniae (13%) were the most common agents identified. Other Gram-negative bacilli, Mycobacterium tuberculosis, Chlamydia pneumoniae each accounted for 5%. The bacteria presented wild type antibiotic susceptibility profiles. Forty-four percent of subjects were high-risk patients (PSI class IV-V). The mortality rate (30%) was significantly associated with disease severity score (P<0.001), and with failure to establish an etiological diagnosis (P=0.027). No associations were found between etiology and underlying diseases, PSI class, nor mortality.

conclusionsViruses and Gram-negative bacilli are dominant causes of CAP in this region, more so than S. pneumoniae. Most of the bacteria have wild type susceptibility to antimicrobial agents. Patients with severe disease and those with unknown etiology have a higher mortality risk.

Indexed as

AgedBacteriaCohort StudiesCommunity-Acquired InfectionsFemaleGram-Negative BacteriaGram-Negative Bacterial InfectionsHumansIndonesiaKlebsiella pneumoniaeMaleMiddle AgedOrthomyxoviridaePneumonia, BacterialPneumonia, ViralProspective StudiesAsiaCommunity-aquired pneumoniaEtiologyGram-negative bacilliTuberculosisVirus

Identifiers

PMID26255889
PMCPMC7110756
OpenAlexW1897581940

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.