ArticleScientific reports2015
Feeding regulates sex pheromone attraction and courtship in Drosophila females.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 85 citations in OpenAlex.
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- Drosophila melanogaster Fly Odors Alone are not Sufficient to Attract other Flies.Journal of chemical ecology · 2026Article
- Diet acts on sexual behavior development in a male moth.Insect science · 2025Article
- An integrated anatomical, functional and evolutionary view of the Drosophila olfactory system.EMBO reports · 2025Article
- Neuroecology of alcohol risk and reward: Methanol boosts pheromones and courtship success inScience advances · 2025Article
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- A brief history of insect neuropeptide and peptide hormone research.Cell and tissue research · 2025Review
- An integrated anatomical, functional and evolutionary view of thebioRxiv : the preprint server for biology · 2025Article
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- The diverse roles of insulin signaling in insect behavior.Frontiers in insect science · 2024Review
- The synaptic basis for sexual dimorphism in the invertebrate nervous system.Current opinion in neurobiology · 2023Review
- Pheromone Perception in Fish: Mechanisms and Modulation by Internal Status.Integrative and comparative biology · 2023Review
- Attraction ofInsects · 2023Article
- Drosophila Free-Flight Odor Tracking is Altered in a Sex-Specific Manner By Preimaginal Sensory Exposure.Journal of chemical ecology · 2023Article
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- Insulin-like peptide 8 (Ilp8) regulates female fecundity in flies.Frontiers in cell and developmental biology · 2023Article
- Neural Control of Action Selection Among Innate Behaviors.Neuroscience bulletin · 2022Review
- A dopamine-gated learning circuit underpins reproductive state-dependent odor preference ineLife · 2022Article
- LiveInsects · 2022Article
- Endocrine cybernetics: neuropeptides as molecular switches in behavioural decisions.Open biology · 2022Review
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Drosophila melanogaster, gender-specific behavioural responses to the male-produced sex pheromone cis-vaccenyl acetate (cVA) rely on sexually dimorphic, third-order neural circuits. We show that nutritional state in female flies modulates cVA perception in first-order olfactory neurons. Starvation increases, and feeding reduces attraction to food odour, in both sexes. Adding cVA to food odour, however, maintains attraction in fed females, while it has no effect in males. Upregulation of sensitivity and behavioural responsiveness to cVA in fed females is paralleled by a strong increase in receptivity to male courtship. Functional imaging of the antennal lobe (AL), the olfactory centre in the insect brain, shows that olfactory input to DA1 and VM2 glomeruli is also modulated by starvation. Knocking down insulin receptors in neurons converging onto the DA1 glomerulus suggests that insulin-signalling partly controls pheromone perception in the AL, and adjusts cVA attraction according to nutritional state and sexual receptivity in Drosophila females.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.