Evidence map›Paper›PMID 26255704›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Effectiveness of the prevention of mother-to-child HIV transmission in Bahia, Brazil.

Fátima Rejane Lemos Patricio, George Williams Rutherford, José Henrique Silva Barreto, Cynthia Rodamilans, Roberto Badaró

Abstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fátima Rejane Lemos PatricioSpecialty Center for Diagnosis, Care and Research, Salvador, BA, Brazil.
George Williams RutherfordGlobal Health Sciences, University of California, San Francisco, USA. Electronic address: george.rutherford@ucsf.edu.
José Henrique Silva BarretoSpecialty Center for Diagnosis, Care and Research, Salvador, BA, Brazil.
Cynthia RodamilansSpecialty Center for Diagnosis, Care and Research, Salvador, BA, Brazil.
Roberto BadaróDivision of Infectious Diseases, Universidade Federal da Bahia (UFBA), Salvador, BA, Brazil.

Funding

ICOHRTA Visiting Scientists ProgramD43TW005799 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RUTHERFORD, GEORGE WILLIAMS · 2001 to 2011
$2.5M
FIC NIH HHS D43 TW05799
6 · The paper itself

Abstract

introductionAntiretroviral therapy and prophylaxis during the antepartum, intrapartum and postpartum periods, cesarean delivery and avoidance of breast milk significantly reduce vertical transmission of HIV.

objectiveTo evaluate the effectiveness prevention of mother-to-child transmission of HIV and determine the rate of vertical transmission in a public sexually transmitted infection and HIV referral center in Salvador, Bahia, in the period immediately prior to the initiation of universal antiretroviral therapy in pregnant women.

methodsCross-sectional study using data collected from medical records of children born to HIV infected mothers in Bahia from 2005 to 2008 who were referred to the Reference Center for Diagnosis and Research of Sexually Transmitted Diseases and HIV/AIDS for care.

resultsOf 232 HIV-exposed infants, 19 (8.2%) had confirmed HIV infection. One hundred eighty-eight (81%) mothers received antenatal care, 120 (52%) antepartum antiretroviral therapy or prophylaxis, and 168 (72%) intrapartum zidovudine. Two hundred twenty-three (96%) infants received zidovudine. In multivariable models, the combination of intrapartum and postpartum antiretroviral prophylaxis was associated with decreased adjusted odds of mother-to-child transmission.

conclusionsLow levels of antenatal screening and access to prevention of mother-to-child transmission were significant limitations in the cascade of prevention of mother-to-child transmission at our center in this period.

Indexed as

AdultAnti-HIV AgentsBrazilCross-Sectional StudiesFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousTreatment OutcomeAnti-HIV AgentsBrazilEffectivenessHIVVertical transmission

Identifiers

PMID26255704
PMCPMC9427510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.