ArticleAmerican journal of ophthalmology2015
The Association of Race With Childhood Uveitis.
Article in American journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Characteristics Associated with Appointment No-Show at an Academic Uveitis Service.Ocular immunology and inflammation · 2026Article
- Adalimumab to treat noninfectious pediatric chronic anterior uveitis: a case series.International ophthalmology · 2024Article
- Paediatric Uveitis - the uniqueness in clinical presentation and the efficacy of biologics treatment.Journal of ophthalmic inflammation and infection · 2024Article
- Sociodemographic and Visual Outcomes of Juvenile Idiopathic Arthritis Uveitis: IRISClinical ophthalmology (Auckland, N.Z.) · 2024Article
- Assessing the Validity and Reliability of the Effects of Youngsters' Eyesight on Quality of Life Questionnaire Among Children With Uveitis.Arthritis care & research · 2022Article
- Traumatic Intralenticular Neovascularization in a HLA B27+ Pediatric Patient.Diagnostics (Basel, Switzerland) · 2021Article
- Paediatric non-infectious uveitis in Cape Town, South Africa: a retrospective review of disease characteristics and outcomes on immunomodulating treatment.Pediatric rheumatology online journal · 2021Observational
- Characteristics, evolution, and outcome of patients with non-infectious uveitis referred for rheumatologic assessment and management: an Egyptian multicenter retrospective study.Clinical rheumatology · 2021Article
- Brolucizumab in Neovascular Age-Related Macular Degeneration - Indian Real-World Experience: The BRAILLE Study.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Timing of infliximab and adalimumab initiation despite methotrexate in children with chronic non-infectious anterior uveitis.Eye (London, England) · 2019Article
- Incidence and predictors of Uveitis in juvenile idiopathic arthritis in a Nordic long-term cohort study.Pediatric rheumatology online journal · 2017Article
- Uveitis in children.Current opinion in rheumatology · 2016Review
- Patterns of Intermediate Uveitis in Children Presenting at a Tertiary Eye Care Center in South India.Middle East African journal of ophthalmologyArticle
- Follow-Up Adherence for Patients with Juvenile Idiopathic Arthritis-Associated Uveitis at a Tertiary Care Center.Journal of current ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo identify risk factors for a severe uveitis course among children with noninfectious uveitis.
designRetrospective cohort study.
methodThis was a retrospective analysis of a prospectively collected database. Records of 94 children with uveitis were reviewed at enrollment and every 3-6 months (2011-2015). Severe uveitis was defined as a history of ocular complications or a visual acuity (VA) of ≤20/200. Children were compared by disease, VA, complications, and race. Regression models were used to model risk factors for severe disease. When examining race, we focused on non-Hispanic African-American and non-Hispanic white children only.
resultsOf 85 children with uveitis and complete ocular examinations, 27 (32%) had a history of a VA of ≤20/200. A subanalysis of non-Hispanic African-American and white children showed an increased prevalence of VA ≤20/200 in non-Hispanic African-Americans (18/25; 72% vs 4/43; 9%). Non-Hispanic African-Americans were more likely to be diagnosed at an older age (P = .030) and to have intermediate uveitis (P = .026), bilateral disease (P = .032), a history of VA ≤20/50 (P = .002), VA ≤20/200 (P < .001), and a higher rate of complications (P < .001). On multivariable analysis, non-Hispanic African-American race was a significant predictor of blindness (OR = 31.6, 95% CI 5.9-168.5, P < .001), after controlling for uveitis duration. Non-Hispanic African-Americans also developed 2.2 times more unique complications per year of disease than non-Hispanic whites when controlling for uveitis type and duration.
conclusionsThere appear to be racial differences in the outcomes of children with uveitis. Non-Hispanic African-American children with non-juvenile idiopathic arthritis-associated uveitis may have worse visual outcomes with increased vision loss and ocular complications. These findings highlight the need for future studies in minority populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.