Evidence map›Paper›PMID 26255305›Full record

ReviewNeuropsychology review2015

Diffusion MRI and its Role in Neuropsychology.

Bryon A Mueller, Kelvin O Lim, Laura Hemmy, Jazmin Camchong

Abstract readReview
In one paragraph

Review in Neuropsychology review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  16. Down to earth - A new type of hygiene.Biomedical journal · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bryon A MuellerDepartment of Psychiatry, Medical School, University of Minnesota, 717 Delaware St SE, Suite 516, Minneapolis, MN, 55414, USA.
Kelvin O Lim
Laura Hemmy
Jazmin Camchong

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NMR Imaging and SpectroscopyP41EB015894 · NIBIB · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2017
$8.4M
Role of impaired cognitive states & risk factors in conversion to mixed dementiasR01AG038651 · NIA · UNIVERSITY OF KENTUCKY · PI ABNER, ERIN, KRYSCIO, RICHARD J. · 2011 to 2023
$6.1M
Institutional Center Cores for Advanced NeuroimagingP30NS076408 · NINDS · UNIVERSITY OF MINNESOTA · PI UGURBIL, KAMIL · 2012 to 2020
$4.2M
Neuropathologic research on dementia using Nun Study and HAAS dataU01AG046871 · NIA · UNIVERSITY OF WASHINGTON · PI MONTINE, THOMAS J, WHITE, LON RAY · 2013 to 2015
$2.0M
Noninvasive Antioxidant Quantification in the Human Brain under Oxidative StressR01AG039396 · NIA · UNIVERSITY OF MINNESOTA · PI TERPSTRA, MELISSA J · 2012 to 2016
$1.6M
NIA NIH HHS R01 AG038651NIA NIH HHS R01AG038651-01A1NIA NIH HHS R01 AG039396NIA NIH HHS R01AG039396NIA NIH HHS R01AG386561NIA NIH HHS U01 AG046871NIA NIH HHS U01AG046871NIBIB NIH HHS P41 EB015894NIMH NIH HHS 1U54MH091657NIMH NIH HHS U54 MH091657NINDS NIH HHS P30 NS076408
6 · The paper itself

Abstract

Diffusion Magnetic Resonance Imaging (dMRI) is a popular method used by neuroscientists to uncover unique information about the structural connections within the brain. dMRI is a non-invasive imaging methodology in which image contrast is based on the diffusion of water molecules in tissue. While applicable to many tissues in the body, this review focuses exclusively on the use of dMRI to examine white matter in the brain. In this review, we begin with a definition of diffusion and how diffusion is measured with MRI. Next we introduce the diffusion tensor model, the predominant model used in dMRI. We then describe acquisition issues related to acquisition parameters and scanner hardware and software. Sources of artifacts are then discussed, followed by a brief review of analysis approaches. We provide an overview of the limitations of the traditional diffusion tensor model, and highlight several more sophisticated non-tensor models that better describe the complex architecture of the brain's white matter. We then touch on reliability and validity issues of diffusion measurements. Finally, we describe examples of ways in which dMRI has been applied to studies of brain disorders and how identified alterations relate to symptomatology and cognition.

Indexed as

ArtifactsBrainDiffusion Magnetic Resonance ImagingDiffusion Tensor ImagingHumansImage Processing, Computer-AssistedNeural PathwaysNeuropsychologyReproducibility of ResultsWhite Matter

Identifiers

PMID26255305
PMCPMC4807614

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.