Evidence map›Paper›PMID 26254893›Full record

SynthesisJournal of autism and developmental disorders2016

Association Between Maternal Obesity and Autism Spectrum Disorder in Offspring: A Meta-analysis.

Ya-Min Li, Jian-Jun Ou, Li Liu, Dan Zhang, Jing-Ping Zhao, Si-Yuan Tang

Open access · bronzeAbstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 8 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 8 syntheses or guidelines pooled it, 103 citations in OpenAlex.

  1. Pooled it
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  7. Maternal pre-pregnancy obesity and child neurodevelopmental outcomes: a meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018
    Pooled it
  8. Pooled it
  9. Article
  10. Review
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  13. Sex-Based Differences in Prenatal and Perinatal Predictors of Autism Spectrum Disorder Using Machine Learning With National Health Data.Autism research : official journal of the International Society for Autism Research · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ya-Min LiThe Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Jian-Jun OuThe Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Li LiuXiangya Nursing School, Central South University, Changsha, Hunan Province, China.
Dan ZhangXiangya Nursing School, Central South University, Changsha, Hunan Province, China.
Jing-Ping ZhaoThe Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China.
Si-Yuan TangXiangya Nursing School, Central South University, Changsha, Hunan Province, China. tangsyuan@126.com.
Central South University · CNSecond Xiangya Hospital of Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the link between maternal obesity and risk of autism among offspring is unclear, the present study assessed this association. A systematic search of an electronic database was performed to identify observational studies that examined the association between maternal obesity and autism. The outcome measures were odds ratios comparing offspring autism risk between obese and normal-weight mothers. Five observational studies were included in the meta-analysis. A fixed-effects model was used since low heterogeneity was observed between studies. The pooled adjusted odds ratio was 1.47 (95 % CI 1.24-1.74). The meta-analysis results support an increased risk of autism spectrum disorder in children of women who were obese during pregnancy. However, further study is warranted to confirm these results.

Indexed as

Maternal HealthAdultAutism Spectrum DisorderChildCohort StudiesFemaleHumansObesityPregnancyPrenatal Exposure Delayed EffectsRisk FactorsAutism spectrum disorderMaternal obesityMeta-analysisOffspring

Identifiers

PMID26254893
OpenAlexW1808780225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.