Evidence map›Paper›PMID 26254802›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016

Pain acts through fatigue to affect participation in individuals with multiple sclerosis.

Shahnaz Shahrbanian, Pierre Duquette, Sara Ahmed, Nancy E Mayo

Abstract read
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In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Combined upper limb and breathing exercise programme for pain management in ambulatory and non-ambulatory multiple sclerosis individuals: part II analyses from feasibility study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
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  7. In support of an individualized approach to assessing quality of life: comparison between Patient Generated Index and standardized measures across four health conditions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shahnaz ShahrbanianFaculty of Medicine, School of Physical and Occupational Therapy, McGill University Health Center, McGill University, Royal Victoria Hospital Site, Ross Pavilion R4.27, 687 Pine Ave W, Montreal, QC, H3A 1A1, Canada. shahnaz.shahrbanian@mail.mcgill.ca.
Pierre DuquetteNotre-Dame Hospital (CHUM), University of Montreal, Montreal, Canada.
Sara AhmedFaculty of Medicine, School of Physical and Occupational Therapy, McGill University Health Center, McGill University, Royal Victoria Hospital Site, Ross Pavilion R4.27, 687 Pine Ave W, Montreal, QC, H3A 1A1, Canada.
Nancy E MayoFaculty of Medicine, School of Physical and Occupational Therapy, McGill University Health Center, McGill University, Royal Victoria Hospital Site, Ross Pavilion R4.27, 687 Pine Ave W, Montreal, QC, H3A 1A1, Canada.

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

purposeThe symptoms of multiple sclerosis (MS) often cause physical and mental dysfunction, which interferes with a person's ability to participate in life's roles. Identification of the strength of the contributors to participation would help prioritize intervention approaches for its improvement. The objective of this study was to estimate the extent to which pain and other MS-related symptoms, physical function, psychological variables, and individual characteristics predict participation in people with MS.

methodsThis was a cross-sectional study. Study sample was a center-stratified random sample of 188 persons with MS. Subjects completed a battery of self-report and performance-based measures that assessed participation and domains affecting participation. To model the relationships among variables, a conceptual framework based on the Wilson and Cleary model was tested. Structural equation modeling aimed at identification of the predictors of participation within the hypothesized theoretical model.

resultsFatigue (β = 0.63, p < 0.0001), physical function (β = 0.37, p < 0.0001), and psychological variables (β = 0.15, p = 0.04) were found to be as significant direct predictors of participation. Pain (β = 0.4, p < 0.0001) and age (β = 0.12, p < 0.0001) were significant indirect predictors through fatigue and physical function, respectively. Together these effects explained 88 % of the variance of participation, 35 % of the variance in psychological variables, and 29 % of the variance in physical function.

conclusionFatigue, physical function, pain, and psychological variables were most important contributors for participation in persons with MS.

Indexed as

AdultCross-Sectional StudiesExerciseFatigueFemaleHumansMaleMultiple SclerosisPainPain MeasurementPhysical FitnessQuality of LifeFatigueMultiple sclerosisPainParticipationRehabilitationStructural equation modelingWilson–Cleary model

Identifiers

PMID26254802

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.