Evidence map›Paper›PMID 26254303›Full record

ArticleJournal of the American Heart Association2015

Distribution of Short-Term and Lifetime Predicted Risks of Cardiovascular Diseases in Peruvian Adults.

Renato Quispe, Juan Carlos Bazo-Alvarez, Melissa S Burroughs Peña, Julio A Poterico, Robert H Gilman, William Checkley, Antonio Bernabé-Ortiz, Mark D Huffman, J Jaime Miranda, PERU MIGRANT Study and 1 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Renato QuispeCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru (R.Q., J.C.B.A., M.S.B.P., J.A.P., A.B.O., J.M.).
Juan Carlos Bazo-AlvarezCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru (R.Q., J.C.B.A., M.S.B.P., J.A.P., A.B.O., J.M.).
Melissa S Burroughs PeñaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru (R.Q., J.C.B.A., M.S.B.P., J.A.P., A.B.O., J.M.) Duke University Research Institute, Duke University, Durham, NC (M.S.B.P.).
Julio A PotericoCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru (R.Q., J.C.B.A., M.S.B.P., J.A.P., A.B.O., J.M.).
Robert H GilmanAsociación Benéfica PRISMA, Lima, Peru (R.H.G.) Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (R.H.G., W.C.).
William CheckleyDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (R.H.G., W.C.) Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD (W.C.).
Antonio Bernabé-OrtizCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru (R.Q., J.C.B.A., M.S.B.P., J.A.P., A.B.O., J.M.).
Mark D HuffmanDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL (M.D.H.).
J Jaime MirandaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru (R.Q., J.C.B.A., M.S.B.P., J.A.P., A.B.O., J.M.) Department of Medicine, School of Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru (J.M.).
PERU MIGRANT Study
CRONICAS Cohort Study Group

Funding

Mentoring and Patient Oriented Research in AsthmaK24ES021098 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI DIETTE, GREGORY B · 2012 to 2016
$927k
Medical Research Council MR/K006584/1Medical Research Council MR/K007467/1NIEHS NIH HHS K24 ES021098Wellcome Trust 098504
6 · The paper itself

Abstract

backgroundShort-term risk assessment tools for prediction of cardiovascular disease events are widely recommended in clinical practice and are used largely for single time-point estimations; however, persons with low predicted short-term risk may have higher risks across longer time horizons. METHODS AND

resultsWe estimated short-term and lifetime cardiovascular disease risk in a pooled population from 2 studies of Peruvian populations. Short-term risk was estimated using the atherosclerotic cardiovascular disease Pooled Cohort Risk Equations. Lifetime risk was evaluated using the algorithm derived from the Framingham Heart Study cohort. Using previously published thresholds, participants were classified into 3 categories: low short-term and low lifetime risk, low short-term and high lifetime risk, and high short-term predicted risk. We also compared the distribution of these risk profiles across educational level, wealth index, and place of residence. We included 2844 participants (50% men, mean age 55.9 years [SD 10.2 years]) in the analysis. Approximately 1 of every 3 participants (34% [95% CI 33 to 36]) had a high short-term estimated cardiovascular disease risk. Among those with a low short-term predicted risk, more than half (54% [95% CI 52 to 56]) had a high lifetime predicted risk. Short-term and lifetime predicted risks were higher for participants with lower versus higher wealth indexes and educational levels and for those living in urban versus rural areas (P<0.01). These results were consistent by sex.

conclusionsThese findings highlight potential shortcomings of using short-term risk tools for primary prevention strategies because a substantial proportion of Peruvian adults were classified as low short-term risk but high lifetime risk. Vulnerable adults, such as those from low socioeconomic status and those living in urban areas, may need greater attention regarding cardiovascular preventive strategies.

Indexed as

AdultAgedAge FactorsAlgorithmsCardiovascular DiseasesEducational StatusFemaleHumansIncomeMaleMiddle AgedPeruPrevalenceResidence CharacteristicsRisk AssessmentRisk Factorscardiovascular risklifetime cardiovascular riskPooled Cohort Risk Equationsrisk estimation toolsshort‐term cardiovascular risk

Identifiers

PMID26254303
PMCPMC4599468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.