Evidence map›Paper›PMID 26254146›Full record

ArticleTrends in immunology2015

Do not scratch that mole!

Mark Jelcic, Philipp Niethammer

Open access · greenAbstract readComment
In one paragraph

Article in Trends in immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. DHRS7 Integrates NADPbioRxiv : the preprint server for biology · 2025
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mark JelcicCell Biology Program, Memorial Sloan Kettering Cancer Center, 411 E 67th Street, New York, NY 10065, USA.
Philipp NiethammerCell Biology Program, Memorial Sloan Kettering Cancer Center, 411 E 67th Street, New York, NY 10065, USA. Electronic address: niethamp@mskcc.org.
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Regulation of Wound Detection in Animal TissuesR01GM099970 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI NIETHAMMER, PHILIPP MICHAEL · 2012 to 2020
$3.2M
NCI NIH HHS P30 CA008748NIGMS NIH HHS GM099970NIGMS NIH HHS R01 GM099970
6 · The paper itself

Abstract

Nevi harbor some of the same oncogene mutations that also drive malign melanoma. Further tumor promoting events are required to unleash their carcinogenic potential. Using zebrafish whose melanocytes overexpress an HRAS-oncogene, a new study reports that injury induces melanoma, possibly through recruitment of neutrophils that trigger proliferation of preneoplastic melanocytes.

Indexed as

AnimalsHumansMelanomaNeoplasms, ExperimentalPrecancerous ConditionsWounds and InjuriesZebrafish

Identifiers

PMID26254146
PMCPMC4567386
OpenAlexW1670932321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.