Evidence map›Paper›PMID 26254053›Full record

ArticleThe Journal of allergy and clinical immunology2015

Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy.

Lisa M Wheatley, Marshall Plaut, Julie M Schwaninger, Aleena Banerji, Mariana Castells, Fred D Finkelman, Gerald J Gleich, Emma Guttman-Yassky, Simon A K Mallal, Dean J Naisbitt and 7 more

Abstract readConsensus Development Conference, NIH
In one paragraph

Article in The Journal of allergy and clinical immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Drug hypersensitivity reactions: review of the state of the science for prediction and diagnosis.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Are you sure that it is a drug allergy?Clinical and experimental pediatrics · 2020
    Article
  10. Article
  11. Article
  12. Controversies in Drug Allergy: Drug Allergy Pathways.The journal of allergy and clinical immunology. In practice · 2019
    Review
  13. Diagnosing and managing drug allergy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2018
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Pro and Contra: Provocation Tests in Drug Hypersensitivity.International journal of molecular sciences · 2017
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 16 institutions in 5 countries.

Lisa M WheatleyDivision of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md. Electronic address: lisa.wheatley@nih.gov.
Marshall PlautDivision of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Julie M SchwaningerDivision of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Md.
Aleena BanerjiDivision of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, Mass.
Mariana CastellsDrug Hypersensitivity and Desensitization Center, Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Boston, Mass.
Fred D FinkelmanDivision of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, University of Cincinnati College of Medicine, the Department of Medicine, Cincinnati Veterans Affairs Medical Center, and the Division of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Gerald J GleichDepartments of Dermatology and Internal Medicine, University of Utah, Salt Lake City, Utah.
Emma Guttman-YasskyDepartment of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai Medical Center, New York, NY.
Simon A K MallalCenter for Translational Immunology and Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn; Institute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia.
Dean J NaisbittMedical Research Council Centre for Drug Safety Science, Department of Pharmacology, University of Liverpool, Liverpool, United Kingdom.
David A OstrovDepartment of Pathology, Immunology and Laboratory Medicine, Division of Experimental Pathology, University of Florida College of Medicine, Gainesville, Fla.
Elizabeth J PhillipsInstitute for Immunology and Infectious Diseases, Murdoch University, Murdoch, Australia; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Werner J PichlerADR-AC GMBH, Holligenstr. 91, CH 3008, Bern, Switzerland.
Thomas A E Platts-MillsAsthma and Allergic Diseases Center, Department of Medicine, University of Virginia, Charlottesville, Va.
Jean-Claude RoujeauUniversité Paris-Est Créteil, 94010, Créteil, France.
Lawrence B SchwartzDivision of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Va.
Lauren A TrepanierDepartment of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wis.
National Institutes of Health · USADR-AC (Switzerland) · CHBrigham and Women's Hospital · USCincinnati Children's Hospital Medical Center · USIcahn School of Medicine at Mount Sinai · USMassachusetts General Hospital · USNational Institute of Allergy and Infectious Diseases · USUniversité Paris-Est Créteil · FRUniversity of Florida · USUniversity of Liverpool · GBUniversity of Utah · USUniversity of Virginia · USUniversity of Wisconsin–Madison · USVanderbilt University · USVanderbilt University Medical Center · USVirginia Commonwealth University · US

Funding

Intramural NIH HHS Z99 AI999999
6 · The paper itself

Abstract

Allergic reactions to drugs are a serious public health concern. In 2013, the Division of Allergy, Immunology, and Transplantation of the National Institute of Allergy and Infectious Diseases sponsored a workshop on drug allergy. International experts in the field of drug allergy with backgrounds in allergy, immunology, infectious diseases, dermatology, clinical pharmacology, and pharmacogenomics discussed the current state of drug allergy research. These experts were joined by representatives from several National Institutes of Health institutes and the US Food and Drug Administration. The participants identified important advances that make new research directions feasible and made suggestions for research priorities and for development of infrastructure to advance our knowledge of the mechanisms, diagnosis, management, and prevention of drug allergy. The workshop summary and recommendations are presented herein.

Indexed as

AbacavirCarbamazepineDideoxynucleosidesDrug HypersensitivityGene ExpressionHaptensHLA AntigensHumansImmunoglobulin ENational Institute of Allergy and Infectious Diseases (U.S.)Practice Guidelines as TopicReceptors, Antigen, T-CellStevens-Johnson SyndromeTerminology as TopicTranslational Research, BiomedicalUnited StatesAbacavirCarbamazepineDideoxynucleosidesHaptensHLA AntigensImmunoglobulin EReceptors, Antigen, T-Cellaltered peptide repertoire hypothesisdesensitizationDrug allergydrug hypersensitivityhapten hypothesispharmacogenomicspharmacologic interaction with immune receptor hypothesisStevens-Johnson syndrometoxic epidermal necrolysis

Identifiers

PMID26254053
PMCPMC4529958
OpenAlexW2105460497

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.