ArticleObesity surgery2016
Elipse™, a Procedureless Gastric Balloon for Weight Loss: a Proof-of-Concept Pilot Study.
Article in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- The Efficacy and Safety of a Procedureless Gastric Balloon for Weight Loss: a Systematic Review and Meta-Analysis.Obesity surgery · 2020Pooled it
- Effect of Swallow Balloon Therapy with the Combination of Semaglutide Oral Formulation: a Randomised Double-Blind Single-Centre Study.Obesity surgery · 2024Trial
- A Randomized, Controlled Trial Comparing the Impact of a Low-Calorie Ketogenic vs a Standard Low-Calorie Diet on Fat-Free Mass in Patients Receiving an Elipse™ Intragastric Balloon Treatment.Obesity surgery · 2021Trial
- Trial
- Article
- Endoscopic Bariatric Therapies in Inflammatory Bowel Disease: Patient Selection, Nutritional Risk, and Periprocedural Management.Metabolites · 2026Review
- Exploratory Machine Learning Methods to Assess a Novel Individualized Lifestyle Intervention on Weight and Body Composition with or Without a Swallowable Intragastric Balloon.Obesity surgery · 2025Article
- Endoscopic bariatrics: Current status and emerging technologies.World journal of gastrointestinal endoscopy · 2025Review
- Weight Loss Maintenance 1 Year after the Swallowable Gastric Balloon: Results from an International Multicenter Study.Obesity surgery · 2025Article
- Burst that Bubble. Gastric Perforation from an Ingested Intragastric Balloon: A Case Report.Clinical practice and cases in emergency medicine · 2024Article
- Successful Weight Loss in Adolescents with Overweight or Obesity Using a Swallowable Intragastric Balloon and Nutritional Oversight.Obesity surgery · 2024Article
- Overview on the endoscopic treatment for obesity: A review.World journal of gastroenterology · 2023Review
- Surgical Management of Intra-gastric Balloon Complications, Single-Center Experience, and Literature Review.Obesity surgery · 2023Review
- Six intragastric balloons: Which to choose?World journal of gastrointestinal endoscopy · 2021Review
- Endoscopy Management of Complete Gastric Outlet Obstruction Secondary to Elipse™ Intragastric Balloon.Cureus · 2021Article
- Outcomes of a Swallowable Intragastric Balloon (Elipse™) on 96 Overweight and Obese Patients.Obesity surgery · 2021Article
- The Clinical and Metabolic Effects of Intragastric Balloon on Morbid Obesity and Its Related Comorbidities.Clinical endoscopy · 2021Article
- Ultrasound-guided insertion of the ElipseJournal of ultrasound · 2020Article
- [Intragastric balloon for weight reduction: rationale, benefits, risks and indications].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Laparoscopic management of a migrated intragastric balloon causing mechanical small bowel obstruction: a case report and review of the literature.Annals of the Royal College of Surgeons of England · 2019Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic gastric balloons have been used effectively as weight loss devices for decades, but the requirement for endoscopy and sedation poses several limitations. The goal of this pilot study was to evaluate the safety and performance of a prototype version of Elipse™, a procedureless gastric balloon.
methodsEight patients (mean BMI = 31.0 kg/m(2)) participated in this study. Each patient swallowed one Elipse™ balloon intended to remain in the stomach for 6 weeks, self-empty, and then pass. Each balloon was filled with 450 mL of filling fluid. Patients returned every 2 weeks for abdominal ultrasound. No specific diet or exercise plan was prescribed.
resultsAll eight patients successfully swallowed the device. The most common adverse events were nausea and vomiting. There were no serious adverse events, and all balloons were excreted safely. Despite not being prescribed a diet or exercise plan, all eight patients lost weight. In 6/8 patients, the balloon remained full through 6 weeks, self-emptied, and passed. In one patient, the balloon appeared partially collapsed on ultrasound after 11 days and was endoscopically punctured. One asymptomatic patient elected to have the balloon endoscopically punctured after 19 days. Both balloons passed in the stool after 4 days. In both cases, endoscopic examination of the upper GI tract showed no abnormalities.
conclusionsThis pilot study demonstrates the safety and performance of Elipse™, a procedureless gastric balloon for weight loss. Future studies will test a commercial design filled to 550 mL intended to last in the stomach for at least 12 weeks.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.