Evidence map›Paper›PMID 26253697›Full record

ArticleAnnals of epidemiology2015

Cognitive decline and the neighborhood environment.

Philippa J Clarke, Jennifer Weuve, Lisa Barnes, Denis A Evans, Carlos F Mendes de Leon

Abstract read
In one paragraph

Article in Annals of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Life Course Nature Exposure and Mental Health Outcomes: A Systematic Review and Future Directions.International journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Article
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  6. Racial/ethnic variation of neighborhood social cohesion, loneliness, and cognitive functioning among midlife and older U.S. adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
    Article
  7. Measuring "third places": Comparing neighborhood data for cognitive health research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Philippa J ClarkeInstitute for Social Research, Department of Epidemiology, University of Michigan, Ann Arbor. Electronic address: pjclarke@umich.edu.
Jennifer WeuveDepartment of Internal Medicine, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, Illinois.
Lisa BarnesDepartment of Neurological Sciences, Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois; Department of Behavioral Sciences, Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois.
Denis A EvansDepartment of Internal Medicine, Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, Illinois.
Carlos F Mendes de LeonDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor.

Funding

Risk Factors for Cognitive Decline in African-AmericansR01AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2004 to 2025
$18.2M
Does the Neighborhood Environment Modify Genetic Risk for Cognitive Decline?R03AG042956 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CLARKE, PHILIPPA · 2012 to 2012
$78k
NIA NIH HHS R01 AG022018NIA NIH HHS R03 AG042956NIA NIH HHS R03-AG42956
6 · The paper itself

Abstract

purposeLittle research has looked beyond individual factors to consider the influence of the neighborhood environment on cognitive function. A greater density of physical resources (e.g., recreational centers and parks) and institutional resources (e.g., community centers) may buffer cognitive decline by offering opportunities for physical activity and social interaction.

methodsUsing data from the Chicago Health and Aging Project (1993-2011), a prospective cohort study of 6518 adults of age 65 years or older, we fit a three-level growth curve model to examine the role of individual and neighborhood factors (objectively observed at the block group level) on trajectories of cognitive function (composite of East Boston Memory Test, symbol digit test, and Mini Mental State Examination) in later life.

resultsNet of individual factors, residence in a neighborhood with community resources, proximity to public transit, and public spaces in good condition were associated with slower rates of cognitive decline, possibly by increasing opportunities for social and physical activities or access to destinations that facilitate engagement in activities.

conclusionsThese results highlight the role of neighborhood environments in buffering cognitive decline among older adults aging in place.

Indexed as

CognitionMemoryAgedAged, 80 and overAgingChicagoCognition DisordersFemaleHealth StatusHumansInterviews as TopicLogistic ModelsLongitudinal StudiesMaleNeuropsychological TestsPopulation SurveillanceCognitive functionLongitudinal modelsNeighborhoodsOlder adultsTrajectories

Identifiers

PMID26253697
PMCPMC4609590

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.