ArticleCirculation. Cardiovascular imaging2015
Left Ventricular Systolic Dysfunction by Longitudinal Strain Is an Independent Predictor of Incident Atrial Fibrillation: A Community-Based Cohort Study.
Article in Circulation. Cardiovascular imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Impact of Left and Right Bundle Branch Block on Left Ventricular Systolic Function and Myocardial Mechanics Assessed by Speckle-Tracking Echocardiography and Cardiac Magnetic Resonance Feature Tracking: A Systematic Review and Meta-Analysis.Echocardiography (Mount Kisco, N.Y.) · 2026Pooled it
- Preoperative echocardiographic predictors of atrial fibrillation after coronary artery bypass graft surgery (CABG): a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Prognostic implications of left ventricular strain by speckle-tracking echocardiography in the general population: a meta-analysis.Vascular health and risk management · 2019Pooled it
- The association of night-time systolic blood pressure with ultrasound markers of subclinical cardiac and vascular disease.Blood pressure monitoring · 2017Trial
- Echocardiographic strain imaging and progression of atrial fibrillation in low-risk individuals.International journal of cardiology. Heart & vasculature · 2026Article
- Associations of Integrated Left Ventricular Myocardial Strain Metrics and Incident Atrial Fibrillation.CJC open · 2026Article
- Recent-onset atrial fibrillation: challenges and opportunities.European heart journal · 2026Review
- Role of NLRP3 Inflammasome in Heart Failure Patients Undergoing Cardiac Surgery as a Potential Determinant of Postoperative Atrial Fibrillation and Remodeling: Is SGLT2 Cotransporter Inhibition an Alternative for Cardioprotection?Antioxidants (Basel, Switzerland) · 2024Review
- The incidence and risk factors of atrial high-rate episodes in patients with a dual-chamber pacemaker.Journal of arrhythmia · 2024Article
- Left Atrial Strain and Incident Atrial Fibrillation in Older Adults.The American journal of cardiology · 2023Article
- Subclinical left ventricular systolic dysfunction and incident stroke in the elderly: long-term findings from Cardiovascular Abnormalities and Brain Lesions.European heart journal. Cardiovascular Imaging · 2023Article
- Left Atrial Strain: Clinical Use and Future Applications-A Focused Review Article.Reviews in cardiovascular medicine · 2022Review
- Deep learning automates detection of wall motion abnormalitiesFrontiers in cardiovascular medicine · 2022Article
- Global longitudinal strain predicts atrial fibrillation in individuals without hypertension: A Community-based cohort study.Clinical research in cardiology : official journal of the German Cardiac Society · 2021Article
- Cardiac mechanics and incident ischemic stroke: the Cardiovascular Health Study.Scientific reports · 2021Article
- Comprehensive Echocardiography of Left Atrium and Left Ventricle Using Modern Techniques Helps in Better Revealing Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy.Diagnostics (Basel, Switzerland) · 2021Article
- Cardiac Amyloidosis with Discordant QRS Voltage between Frontal and Precordial Leads.Medicina (Kaunas, Lithuania) · 2021Article
- Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling in the Community.Current cardiology reports · 2021Review
- Association of type 2 diabetes mellitus with the development of new-onset atrial fibrillation in patients with non-ischemic dilated cardiomyopathy: impact of SGLT2 inhibitors.The international journal of cardiovascular imaging · 2021Article
- Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2020Article
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9 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe increasing prevalence of atrial fibrillation (AF) represents a public health issue. Identifying new predictors of AF is therefore necessary to plan preventive strategies. We investigated whether left ventricular (LV) systolic dysfunction by global longitudinal strain (GLS), a predictor of cardiovascular events, may predict new-onset AF in a population setting. METHODS AND
resultsParticipants (n=675; mean age, 71±9 years; 60% women) in sinus rhythm from the population-based Northern Manhattan Study (NOMAS) underwent 2- and 3-dimensional echocardiography as part of the Cardiac Abnormalities and Brain Lesions (CABL) study. LV systolic function was assessed by LV ejection fraction and speckle-tracking GLS. During a mean follow-up of 63.6±18.7 months, 32 (4.7%) new confirmed cases of AF occurred. Lower GLS (adjusted hazard ratio/unit decrease, 1.22; 95% confidence interval, 1.04-1.43; P=0.015) and increased left atrial volume index (LAVi; adjusted hazard ratio/unit increase, 1.12; 95% confidence interval, 1.07-1.17; P<0.001) were significantly associated with incident AF, whereas LV ejection fraction was not (P=0.176). Abnormal GLS (>-14.7%) was associated with risk of new-onset AF with an adjusted hazard ratio of 3.2 (95% confidence interval, 1.4-7.5; P=0.007). The coexistence of abnormal GLS/abnormal LAVi was associated with a 28.6% incidence of AF (adjusted hazard ratio, 12.1; 95% confidence interval, 3.3-44.8; P<0.001) compared with participants with normal GLS/normal LAVi (AF incidence, 2.0%). AF incidence was intermediate in those with either abnormal GLS or abnormal LAVi (9.3% and 11.1%, respectively). GLS prognostic value for incident AF was incremental over risk factors and LAVi.
conclusionsLV systolic dysfunction by GLS was a powerful and independent predictor of incident AF. GLS assessment may improve AF risk stratification in addition to established parameters.
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