SynthesisSchizophrenia bulletin2016
Explicit Time Deficit in Schizophrenia: Systematic Review and Meta-Analysis Indicate It Is Primary and Not Domain Specific.
Synthesis in Schizophrenia bulletin, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Time perception in bipolar disorder: a systematic review.Acta neuropsychiatrica · 2025Pooled it
- Investigation of the pharmacological and circuit basis for psychedelic drug effects on interval timing in mice.Psychopharmacology · 2026Article
- The Temporal Scaffolding of Sensory Organization.Annual review of psychology · 2026Review
- Review
- The Relationship Between Schizotypal Personality Traits and Temporal Discounting: The Role of the Date/Delay Effect.Schizophrenia bulletin · 2025Article
- Bridging the gap between aberrant time processing and cognitive dysfunction in schizophrenia: a potential core feature?Schizophrenia (Heidelberg, Germany) · 2025Review
- Limited Consistency and Strength of Neural Oscillations During Sustained Visual Attention in Schizophrenia.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024Article
- Hippocampal phase precession is preserved under ketamine, but the range of precession across a theta cycle is reduced.Journal of psychopharmacology (Oxford, England) · 2023Article
- Cerebellar transcranial magnetic stimulation in psychotic disorders: intermittent, continuous, and sham theta-burst stimulation on time perception and symptom severity.Frontiers in psychiatry · 2023Article
- Time discrimination and change detection could share a common brain network: findings of a task-based fMRI study.Frontiers in psychology · 2023Article
- Variables influencing conditioning-evoked hallucinations: overview and future applications.Psychological medicine · 2022Review
- Time in schizophrenia: a link between psychopathology, psychophysics and technology.Translational psychiatry · 2022Review
- Perceptual inference, accuracy, and precision in temporal reproduction in schizophrenia.Schizophrenia research. Cognition · 2022Article
- Maternal immune activation alters the sequential structure of ultrasonic communications in male rats.Brain, behavior, & immunity - health · 2021Article
- Hippocampal Sequencing Mechanisms Are Disrupted in a Maternal Immune Activation Model of Schizophrenia Risk.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Timing dysfunction and cerebellar resting state functional connectivity abnormalities in youth at clinical high-risk for psychosis.Psychological medicine · 2021Article
- Dopamine and the interdependency of time perception and reward.Neuroscience and biobehavioral reviews · 2021Review
- Disorganization of Oscillatory Activity in Animal Models of Schizophrenia.Frontiers in neural circuits · 2021Review
- An fMRI Study Using a Combined Task of Interval Discrimination and Oddball Could Reveal Common Brain Circuits of Cognitive Change.Frontiers in psychiatry · 2021Article
- Overexpression of striatal D2 receptors reduces motivation thereby decreasing food anticipatory activity.The European journal of neuroscience · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although timing deficits are a robust finding in schizophrenia (SZ), the notion of a genuine time perception disorder in SZ is still being debated because distortions in timing might depend on neuropsychological deficits that are characteristics of the illness. Here we used meta-analytic methods to summarize the evidence of timing deficits in SZ and moderator analyses to determine whether defective timing in SZ arises from nontemporal sources or from defective time perception. PubMed Services, PsycNET, and Scopus were searched through March 2015, and all references in articles were investigated to find other relevant studies. Studies were selected if they included subjects with a primary diagnosis of SZ compared to a healthy control (HC) group and if they reported behavioral measures of duration estimation (perceptual and motor explicit timing). Data from 24 studies published from 1956 to 2015, which comprised 747 SZ individuals and 808 HC, were included. Results indicate that SZ individuals are less accurate than HC in estimating time duration across a wide range of tasks. Subgroup analyses showed that the fundamental timing deficit in SZ is independent from the length of the to-be-timed duration (automatic and cognitively controlled timing) and from methods of stimuli estimation (perceptual and motor timing). Thus, time perception per se is disturbed in SZ (not just task-specific timing processes) and this perturbation is independent from more generalized cognitive impairments. Behavioral evidence of disturbed automatic timing should be more thoroughly investigated with the aim of defining it as a cognitive phenotype for more homogeneous diagnostic subgrouping.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.