Evidence map›Paper›PMID 26253332›Full record

Trial reportTrials2015

Prevention of delirium (POD) for older people in hospital: study protocol for a randomised controlled feasibility trial.

John Young, Francine Cheater, Michelle Collinson, Marie Fletcher, Anne Forster, Mary Godfrey, John Green, Shamaila Anwar, Suzanne Hartley, Claire Hulme and 7 more

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Interventions for preventing delirium in hospitalised non-ICU patients.The Cochrane database of systematic reviews · 2016
    Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Review
  12. Clinical and Epidemiological Approach to Delirium in an Acute Care Unit: A Cross-Sectional Study.International journal of environmental research and public health · 2022
    Article
  13. Article
  14. [Nonpharmaceutical concepts for prevention and treatment of delirium].Zeitschrift fur Gerontologie und Geriatrie · 2021
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

John YoungAcademic Unit of Elderly Care and Rehabilitation, University of Leeds, Bradford Institute for Health Research, Temple Bank House, Bradford Royal Infirmary, Duckworth Lane, Bradford, BD9 6RJ, UK. john.young@bthft.nhs.uk.
Francine CheaterSchool of Nursing Sciences, Faculty of Medicine and Health Sciences, University of East Anglia, Edith Cavell Building, Norwich Research Park, Norwich, NR4 7TJ, UK. f.cheater@uea.ac.uk.
Michelle CollinsonClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK. m.collinson@leeds.ac.uk.
Marie FletcherClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK. m.fletcher@leeds.ac.uk.
Anne ForsterAcademic Unit of Elderly Care and Rehabilitation, University of Leeds, Bradford Institute for Health Research, Temple Bank House, Bradford Royal Infirmary, Duckworth Lane, Bradford, BD9 6RJ, UK. a.forster@leeds.ac.uk.
Mary GodfreyLeeds Institute of Health Sciences, Charles Thackrah Building, 101 Clarendon Road, Leeds, UK. m.godfrey@leeds.ac.uk.
John GreenAcademic Unit of Elderly Care and Rehabilitation, University of Leeds, Bradford Institute for Health Research, Temple Bank House, Bradford Royal Infirmary, Duckworth Lane, Bradford, BD9 6RJ, UK. john.green@bthft.ac.uk.
Shamaila AnwarClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK. s.t.anwar@leeds.ac.uk.
Suzanne HartleyClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK. s.hartley@leeds.ac.uk.
Claire HulmeAcademic Unit of Health Economics, Leeds Institute of Health Science, University of Leeds, Leeds, LS2 9JT, UK. c.t.hulme@leeds.ac.uk.
Sharon K InouyeDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02215, USA. agingbraincenter@hsl.harvard.edu.
David MeadsAcademic Unit of Health Economics, Leeds Institute of Health Science, University of Leeds, Leeds, LS2 9JT, UK. d.meads@leeds.ac.uk.
Gillian SantorelliClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK. g.santorelli@leeds.ac.uk.
Najma SiddiqiLeeds Institute of Health Sciences, Charles Thackrah Building, 101 Clarendon Road, Leeds, UK. n.siddiqi@leeds.ac.uk.
Jane SmithAcademic Unit of Elderly Care and Rehabilitation, University of Leeds, Bradford Institute for Health Research, Temple Bank House, Bradford Royal Infirmary, Duckworth Lane, Bradford, BD9 6RJ, UK. jane.smith@bthft.nhs.uk.
Elizabeth TealeAcademic Unit of Elderly Care and Rehabilitation, University of Leeds, Bradford Institute for Health Research, Temple Bank House, Bradford Royal Infirmary, Duckworth Lane, Bradford, BD9 6RJ, UK. elizabeth.teale@bthft.nhs.uk.
Amanda J FarrinClinical Trials Research Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, LS2 9JT, UK. a.j.farrin@leeds.ac.uk.
University of Leeds · GBBradford Royal Infirmary · GBHarvard University · USUniversity of East Anglia · GB

Funding

Department of Health PB-PG-0610-22068Department of Health RP-PG-0108-10037
6 · The paper itself

Abstract

backgroundDelirium is the most frequent complication among older people following hospitalisation. Delirium may be prevented in about one-third of patients using a multicomponent intervention. However, in the United Kingdom, the National Health Service has no routine delirium prevention care systems. We have developed the Prevention of Delirium Programme, a multicomponent delirium prevention intervention and implementation process. We have successfully carried out a pilot study to test the feasibility and acceptability of implementation of the programme. We are now undertaking preliminary testing of the programme. METHODS/

designThe Prevention of Delirium Study is a multicentre, cluster randomised feasibility study designed to explore the potential effectiveness and cost-effectiveness of the Prevention of Delirium Programme. Sixteen elderly care medicine and orthopaedic/trauma wards in eight National Health Service acute hospitals will be randomised to receive the Prevention of Delirium Programme or usual care. Patients will be eligible for the trial if they have been admitted to a participating ward and are aged 65 years or over. The primary objectives of the study are to provide a preliminary estimate of the effectiveness of the Prevention of Delirium Programme as measured by the incidence of new onset delirium, assess the variability of the incidence of new-onset delirium, estimate the intracluster correlation coefficient and likely cluster size, assess barriers to the delivery of the Prevention of Delirium Programme system of care, assess compliance with the Prevention of Delirium Programme system of care, estimate recruitment and follow-up rates, assess the degree of contamination due to between-ward staff movements, and investigate differences in financial costs and benefits between the Prevention of Delirium Programme system of care and standard practice. Secondary objectives are to investigate differences in the number, severity and length of delirium episodes (including persistent delirium); length of stay in hospital; in-hospital mortality; destination at discharge; health-related quality of life and health resource use; physical and social independence; anxiety and depression; and patient experience. DISCUSSION: This feasibility study will be used to gather data to inform the design of a future definitive randomised controlled trial.

trial registrationISRCTN01187372 . Registered 13 March 2014.

Indexed as

InpatientsAgedAge FactorsClinical ProtocolsCluster AnalysisCost-Benefit AnalysisDeliriumFeasibility StudiesFemaleGeriatric AssessmentHospital CostsHospital MortalityHumansLength of StayMaleResearch Design

Identifiers

PMID26253332
PMCPMC4529724
OpenAlexW2149387504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.