Evidence map›Paper›PMID 26253182›Full record

ArticleContemporary clinical trials2015

A randomized controlled trial of outpatient CAncer REhabilitation for older adults: The CARE Program.

Mackenzi Pergolotti, Allison M Deal, Grant R Williams, Ashley L Bryant, Bryce B Reeve, Hyman B Muss

Open access · greenAbstract read
In one paragraph

Article in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Cancer Rehabilitation and Palliative Care-Exploring the Synergies.Journal of pain and symptom management · 2020
    Article
  6. Article
  7. Article
  8. Review
  9. The Evolution of Gero-Oncology Nursing.Seminars in oncology nursing · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Mackenzi PergolottiCancer Care Quality Training Program, 1102G McGavran-Greenberg Hall, CB# 7411, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Department of Health Policy and Management, 1102G McGavran-Greenberg Hall, CB# 7411, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: pergolot@email.unc.edu.
Allison M DealBiostatistics Core Facility, The University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, 170 Manning Drive, Chapel Hill, NC 27599, USA. Electronic address: Allison_Deal@med.unc.edu.
Grant R WilliamsGeriatric Oncology Program, The University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, 170 Manning Drive, Chapel Hill, NC 27599, USA. Electronic address: Grant.Williams@unchealth.unc.edu.
Ashley L BryantSchool of Nursing, The University of North Carolina at Chapel Hill, Carrington Hall, CB #7460, Chapel Hill, NC 27599-7460, USA. Electronic address: anleak@email.unc.edu.
Bryce B ReeveDepartment of Health Policy and Management, 1101D McGavran-Greenberg Hall, Campus Box 7411, The University of North Carolina at Chapel Hill, Gillings School of Global Public Health, 135 Dauer Drive, Chapel Hill, NC 27599, USA. Electronic address: bbreeve@email.unc.edu.
Hyman B MussGeriatric Oncology Program, The University of North Carolina at Chapel Hill, Lineberger Comprehensive Cancer Center, 170 Manning Drive, Chapel Hill, NC 27599, USA. Electronic address: hyman_muss@med.unc.edu.
University of North Carolina at Chapel Hill · US

Funding

UNC Oncology K12K12CA120780 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WILLIAM Y. KIM · 2007 to 2026
$9.6M
Cancer Training GrantR25CA116339 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BASCH, ETHAN M., REEVE, BRYCE B · 2008 to 2017
$4.0M
NCI NIH HHS K12 CA120780NCI NIH HHS R25 CA116339
6 · The paper itself

Abstract

backgroundLarge numbers of older adults (aged 65years or older) are surviving cancer; however, many survivors report decreased quality of life (QOL) and limitations in activities of daily living (ADL) and instrumental activities of daily living (IADL) both during and after treatment [1-3]. Occupational and physical therapy (OT/PT) are services focused on improving functional status and QOL that are largely unexplored and underutilized in cancer survivorship care [4,5]. METHODS/

designThis is a randomized, single-blind, two-arm, single institution pilot study. Eighty-two patients will be recruited from a university-affiliated outpatient oncology clinic. Inclusion criteria include the following: aged 65years or older, diagnosis of cancer within 5years, English speaking, has at least one functional deficit, and able to safely participate in an outpatient rehabilitation program. Exclusion criteria are: currently receiving rehabilitation or eligible for hospice. Consented patients will be randomized into two groups: (1) the CARE (CAncer REhabilitation) Program consisting of outpatient OT/PT and (2) standard of care. PRIMARY OUTCOME: change in Nottingham Extended Activities of Daily Living (NEADL) scores from baseline to 3months between CARE and control. DISCUSSION: This study is one of the first RCTs aimed at examining the effect of OT/PT in older adults with cancer. If positive, findings from this study will suggest the potential for outpatient OT/PT to improve the functional ability and QOL of older adults with cancer.

Indexed as

Cancer rehabilitationGeriatric oncologyOccupational therapyPhysical therapy

Identifiers

PMID26253182
PMCPMC4740286
OpenAlexW1596644447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.