Evidence map›Paper›PMID 26252811›Full record

ArticleChemical communications (Cambridge, England)2015

Reversible DNA i-motif to hairpin switching induced by copper(II) cations.

Henry Albert Day, Elisé Patricia Wright, Colin John MacDonald, Andrew James Gates, Zoë Ann Ella Waller

Open access · hybridAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. CoInternational journal of molecular sciences · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Henry Albert DaySchool of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. z.waller@uea.ac.uk.
Elisé Patricia Wright
Colin John MacDonald
Andrew James Gates
Zoë Ann Ella Waller
Norwich Research Park · GBNorwich University · USUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L02229X/1
6 · The paper itself

Abstract

i-Motif DNA structures have previously been utilised for many different nanotechnological applications, but all have used changes in pH to fold the DNA. Herein we describe how copper(II) cations can alter the conformation of i-motif DNA into an alternative hairpin structure which is reversible by chelation with EDTA.

Indexed as

Nucleic Acid ConformationCationsCopperDNAEdetic AcidHydrogen-Ion ConcentrationNanotechnologyNucleotide MotifsSolutionsCationsCopperDNAEdetic AcidSolutions

Identifiers

PMID26252811
PMCPMC4563791
OpenAlexW2153377200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.