ArticleThe Plant journal : for cell and molecular biology2015
Factorial combinations of protein interactions generate a multiplicity of florigen activation complexes in wheat and barley.
Article in The Plant journal : for cell and molecular biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
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Who cites it
75 citing papers in PubMed, 136 citations in OpenAlex.
- CsFDL1-CsFTL3 Complex Represses CsFTL3 via Negative Feedback to Fine-Tune Flowering in Chrysanthemum seticuspe.Plant, cell & environment · 2026Article
- Temperature regulation in plants: From molecular mechanisms to climate-resilient crop improvement.Journal of integrative plant biology · 2026Review
- Vernalization regulatory network identifies potential novel functions for genes in the HvVRN2 locus.The New phytologist · 2026Article
- VRN1 genetically acts upstream of FT1 in the flowering regulatory network in temperate grass leaves.Plant communications · 2026Article
- Optimizing Daily Light Integral in Seedling Stage Accelerates Heading and Flowering in Wheat Under LED Lighting.Plants (Basel, Switzerland) · 2026Article
- MicroRNA156 and its targeted SPL genes interact with the photoperiod, vernalization, and gibberellin pathways to regulate wheat heading time.The Plant journal : for cell and molecular biology · 2026Article
- Florigen and cytokinin signaling antagonistically regulate FLOWERING LOCUS T-LIKE1 to drive a florigen relay that facilitates inflorescence development in rice.Science advances · 2025Article
- Fine tuning wheat heading time through genome editing of transcription factor binding sites in Ppd-1 gene promoter.Scientific reports · 2025Article
- Fine-tuning wheat development for the winter to spring transition.Plant communications · 2025Article
- Article
- The FKF1-ELF3-PRC2 module regulates flowering time in response to light in temperate grasses.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Pangenome insights into structural variation and functional diversification of barley CCT motif genes.The plant genome · 2025Article
- Article
- TaFT-D1 positively regulates grain weight by acting as a coactivator of TaFDL2 in wheat.Plant biotechnology journal · 2025Article
- Genome-wide identification and expression analysis of TaFDL gene family responded to vernalization in wheat (Triticum aestivum L.).BMC genomics · 2025Article
- A gain-of-function mutation at the C-terminus of FT-D1 promotes heading by interacting with 14-3-3A and FDL6 in wheat.Plant biotechnology journal · 2025Article
- Multifaceted roles ofFrontiers in plant science · 2025Review
- Breeding potential of Spanish bread wheat landraces: genetic variability in vernalization and photoperiod sensitivity.Frontiers in plant science · 2025Article
- Natural alleles of LEAFY and WAPO1 interact to regulate spikelet number per spike in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Metabolomics, phytohormone and transcriptomics strategies to reveal the mechanism of barley heading date regulation to responds different photoperiod.BMC genomics · 2024Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The FLOWERING LOCUS T (FT) protein is a central component of a mobile flowering signal (florigen) that is transported from leaves to the shoot apical meristem (SAM). Two FT monomers and two DNA-binding bZIP transcription factors interact with a dimeric 14-3-3 protein bridge to form a hexameric protein complex. This complex, designated as the 'florigen activation complex' (FAC), plays a critical role in flowering. The wheat homologue of FT, designated FT1 (= VRN3), activates expression of VRN1 in the leaves and the SAM, promoting flowering under inductive long days. In this study, we show that FT1, other FT-like proteins, and different FD-like proteins, can interact with multiple wheat and barley 14-3-3 proteins. We also identify the critical amino acid residues in FT1 and FD-like proteins required for their interactions, and demonstrate that 14-3-3 proteins are necessary bridges to mediate the FT1-TaFDL2 interaction. Using in vivo bimolecular fluorescent complementation (BiFC) assays, we demonstrate that the interaction between FT1 and 14-3-3 occurs in the cytoplasm, and that this complex is then translocated to the nucleus, where it interacts with TaFDL2 to form a FAC. We also demonstrate that a FAC including FT1, TaFDL2 and Ta14-3-3C can bind to the VRN1 promoter in vitro. Finally, we show that relative transcript levels of FD-like and 14-3-3 genes vary among tissues and developmental stages. Since FD-like proteins determine the DNA specificity of the FACs, variation in FD-like gene expression can result in spatial and temporal modulation of the effects of mobile FT-like signals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.