Evidence map›Paper›PMID 26252517›Full record

ArticlePloS one2015

Psychotropic Drug Use in São Paulo, Brazil--An Epidemiological Survey.

Maria Ines Quintana, Sergio Baxter Andreoli, Marcela Poctich Peluffo, Wagner Silva Ribeiro, Marcelo M Feijo, Rodrigo Affonseca Bressan, Evandro S F Coutinho, Jair de Jesus Mari

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Prevalence of antidepressant use in Brazil: a systematic review with meta-analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2024
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Use of Psychotropic Drugs during the COVID-19 pandemic in Minas Gerais, Brazil.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2023
    Article
  6. Review
  7. Benzodiazepine use in Sao Paulo, Brazil.Clinics (Sao Paulo, Brazil) · 2020
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Maria Ines QuintanaUniversidade Federal de São Paulo-Escola Paulista de Medicina, Psychiatry Department, São Paulo, Brazil.
Sergio Baxter AndreoliUniversidade Federal de São Paulo-Escola Paulista de Medicina, Psychiatry Department, São Paulo, Brazil; Universidade Catolica de Santos, Santos, Brazil.
Marcela Poctich PeluffoUniversidade Catolica de Santos, Santos, Brazil.
Wagner Silva RibeiroUniversidade Federal de São Paulo-Escola Paulista de Medicina, Psychiatry Department, São Paulo, Brazil.
Marcelo M FeijoUniversidade Federal de São Paulo-Escola Paulista de Medicina, Psychiatry Department, São Paulo, Brazil.
Rodrigo Affonseca BressanUniversidade Federal de São Paulo-Escola Paulista de Medicina, Psychiatry Department, São Paulo, Brazil.
Evandro S F CoutinhoEscola Nacional de Saude Publica-Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Jair de Jesus MariUniversidade Federal de São Paulo-Escola Paulista de Medicina, Psychiatry Department, São Paulo, Brazil.
Universidade Federal de São Paulo · BREscola Nacional de Saúde Pública · BRUniversidade Católica de Santos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate the prevalence of one month psychotropic drug use in São Paulo, Brazil, and to assess the gap treatment between the presence of mental disorders and psychotropic drug users.

methodA probabilistic sample of non-institutionalized individuals from the general population of São Paulo (n = 2336; turnout: 84.5%) who were 15 years or older were interviewed by a trained research staff, applying the Composite International Diagnostic Interview 2.1 (CIDI WHO) (depression, anxiety-phobia, OCD\PTSD, alcoholism sections), and an inventory investigating psychotropic drug use during the 12-month and one-month periods immediately preceding the interview. Logistic models were fitted to investigate associations between psychotropic drug use as well as socio-demographic and clinical variables.

resultsThe one month prevalence of psychotropic drug use in São Paulo was 5.89%, the most commonly used drugs were antidepressants (3.15%) and tranquilizers (2.67%). A higher consumption of psychotropic drugs (overall, antidepressants and tranquilizers) was observed among women (OR:2.42), older individuals (OR:1.04), individuals with higher levels of formal education (1.06), and individuals with a family (OR:2.29) or personal history of mental illness (OR:3.27). The main psychotropic drug prescribers were psychiatrists (41%), followed by general practitioners (30%); 60% of psychotropic drugs were obtained through a government-run dispensing program. Most individuals who obtained a positive diagnosis on the CIDI 2.1 during the previous month were not using psychotropic medication (85%). Among individuals with a diagnosis of moderate to severe depression, 67.5% were not on any pharmacological treatment.

conclusionThere is a change in the type of psychotropic more often used in São Paulo, from benzodiazepines to antidepressants, this event is observed in different cultures. The prevalence of use is similar to other developing countries. Most of the patients presenting a psychiatric illness in the month prior to testing were not receiving any sort of psychiatric medication. This may be explained by a failure to identify cases in primary care, which could be improved (and access to treatment could be facilitated) if professionals received more specialized training in managing cases with mental health problems.

Indexed as

AdolescentAdultAgedAntidepressive AgentsAnxietyBenzodiazepinesBrazilDepressionFemaleHumansMaleMiddle AgedObsessive-Compulsive DisorderPrevalenceProbabilityPsychotropic DrugsAntidepressive AgentsBenzodiazepinesPsychotropic Drugs

Identifiers

PMID26252517
PMCPMC4529275
OpenAlexW1939096781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.