Evidence map›Paper›PMID 26252274›Full record

ArticleMedicine2015

Preoperative Computed Tomography to Predict and Stratify the Risk of Severe Pancreatic Fistula After Pancreatoduodenectomy.

Marta Sandini, Davide Paolo Bernasconi, Davide Ippolito, Luca Nespoli, Melissa Baini, Salvatore Barbaro, Davide Fior, Luca Gianotti

Registry-linked trialOpen access · goldAbstract readEvaluation Study
In one paragraph

Article in Medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04582461 (Role of Preoperative Multislice Computed Tomography to Predict the Risk of Pancreatic Fistula After Whipple's Operation.), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04582461 unknown statusnot on this mapstarted 2021, after this paper: background citation

Role of Preoperative Multislice Computed Tomography to Predict the Risk of Pancreatic Fistula After Whipple's Operation.

TypeobservationalSponsorAssiut UniversityRan2021 to 2022Enrolled100ConditionsPancreatic FistulaArmsmultislice computed tomography
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Marta SandiniFrom the Department of Surgery and Translational Medicine (MS, LN, MB, SB, LG), Milano-Bicocca University, San Gerardo Hospital; Department of Health Sciences (DPB), Center of Biostatistics for Clinical Epidemiology, Milano-Bicocca University; Department of Radiology (DI, DF), San Gerardo Hospital, Monza, Italy; and International Research Center in Hepato-Biliary-Pancreatic Diseases, Monza, Italy (LG).
Davide Paolo Bernasconi
Davide Ippolito
Luca Nespoli
Melissa Baini
Salvatore Barbaro
Davide Fior
Luca Gianotti
Department of Medical Sciences · BYUniversity of Milano-Bicocca · ITBridge University · SS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this article is to assess whether measures of abdominal fat distribution, visceral density, and antropometric parameters obtained from computed tomography (CT) may predict postoperative pancreatic fistula (POPF) occurrence.We analyzed 117 patients who underwent pancreatoduodenectomy (PD) and had a preoperative CT scan as staging in our center. CT images were processed to obtain measures of total fat volume (TFV), visceral fat volume (VFV), density of spleen, and pancreas, and diameter of pancreatic duct. The predictive ability of each parameter was investigated by receiver-operating characteristic (ROC) curves methodology and assessing optimal cutoff thresholds. A stepwise selection method was used to determine the best predictive model.Clinically relevant (grades B and C) POPF occurred in 24 patients (20.5%). Areas under ROC-curves showed that none of the parameters was per se significantly predictive. The multivariate analysis revealed that a VFV >2334 cm, TFV >4408 cm, pancreas/spleen density ratio <0.707, and pancreatic duct diameter <5 mm were predictive of POPF. The risk of POPF progressively increased with the number of factors involved and age.It is possible to deduce objective information on the risk of POPF from a simple and routine preoperative radiologic workup.

Indexed as

Decision Support TechniquesPancreaticoduodenectomyPostoperative ComplicationsTomography, X-Ray ComputedAdultAgedBody Fat DistributionFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOutcome Assessment, Health CarePancreasPancreatic Fistula

Identifiers

PMID26252274
PMCPMC4616578
OpenAlexW2261395888

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.