ArticleMolecular medicine (Cambridge, Mass.)2015
Transgenic Expression of miR-222 Disrupts Intestinal Epithelial Regeneration by Targeting Multiple Genes Including Frizzled-7.
Article in Molecular medicine (Cambridge, Mass.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- Long Noncoding RNANon-coding RNA · 2026Article
- Long noncoding RNA GAS5 disrupts intestinal epithelial barrier function by increasing small vault RNA levels.JCI insight · 2026Article
- ceRNA Network Dynamics in Inflammatory Bowel Disease: The LncRNA-miRNA-mRNA Axis in Intestinal Homeostasis and Inflammation.Cell biochemistry and biophysics · 2026Review
- Posttranscriptional Regulation of Intestinal Mucosal Growth and Adaptation by Noncoding RNAs in Critical Surgical Disorders.Journal of investigative surgery : the official journal of the Academy of Surgical Research · 2024Review
- Interaction between microRNA-195 and HuR regulates Paneth cell function in the intestinal epithelium by altering SOX9 translation.American journal of physiology. Cell physiology · 2024Article
- miR-495 promotes intestinal epithelial cell apoptosis through downregulation of Sphingosine-1-phosphate.Physiological reports · 2024Article
- Stabilization ofAmerican journal of physiology. Gastrointestinal and liver physiology · 2023Article
- Activation of Frizzled-7 attenuates blood-brain barrier disruption through Dvl/β-catenin/WISP1 signaling pathway after intracerebral hemorrhage in mice.Fluids and barriers of the CNS · 2021Article
- MicroRNA-195 regulates Tuft cell function in the intestinal epithelium by altering translation of DCLK1.American journal of physiology. Cell physiology · 2021Article
- MicroRNA-222 Regulates Melanoma Plasticity.Journal of clinical medicine · 2020Article
- Long Noncoding RNA H19 Impairs the Intestinal Barrier by Suppressing Autophagy and Lowering Paneth and Goblet Cell Function.Cellular and molecular gastroenterology and hepatology · 2020Article
- miR-222 represses expression of zipcode binding protein-1 and phospholipase C-γ1 in intestinal epithelial cells.American journal of physiology. Cell physiology · 2019Article
- miR-222 enhances radiosensitivity of cancer cells by inhibiting the expression of CD47.International journal of clinical and experimental pathology · 2019Article
- Regulation of Intestinal Epithelial Barrier Function by Long Noncoding RNAMolecular and cellular biology · 2018Article
- α4 Coordinates Small Intestinal Epithelium Homeostasis by Regulating Stability of HuR.Molecular and cellular biology · 2018Article
- MicroRNA in gastrointestinal cell signalling.Inflammopharmacology · 2018Review
- Naturally existing isoforms of miR-222 have distinct functions.Nucleic acids research · 2017Article
- HuR Enhances Early Restitution of the Intestinal Epithelium by Increasing Cdc42 Translation.Molecular and cellular biology · 2017Article
- Posttranscriptional regulation of intestinal epithelial integrity by noncoding RNAs.Wiley interdisciplinary reviews. RNA · 2017Review
- Post-transcriptional regulation of Wnt co-receptor LRP6 and RNA-binding protein HuR by miR-29b in intestinal epithelial cells.The Biochemical journal · 2016Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Defects in intestinal epithelial integrity occur commonly in various pathologies. miR-222 is implicated in many aspects of cellular function and plays an important role in several diseases, but its exact biological function in the intestinal epithelium is underexplored. We generated mice with intestinal epithelial tissue-specific overexpression of miR-222 to investigate the function of miR-222 in intestinal physiology and diseases
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.