ArticleJournal of occupational and environmental hygiene2015
Historical Context and Recent Advances in Exposure-Response Estimation for Deriving Occupational Exposure Limits.
Article in Journal of occupational and environmental hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Derivation of Provisional Chronic Oral Toxicity Values (PCOTV) for Novel Short-Chain PFAS Congeners.Journal of applied toxicology : JAT · 2026Review
- An Integrated AIVIVE-PBPK-QIVIVE Framework with HTTK Validation for Probabilistic Risk Assessment of Neodymium Nitrate.Chemical research in toxicology · 2026Article
- Requirements for occupational exposure limits in psychosocial risk assessment: What we know, what we don't know and what we can learn from other disciplines.Scandinavian journal of work, environment & health · 2025Review
- Comparison of 3 methods characterizing H2S exposure in water and wastewater management work.Annals of work exposures and health · 2024Article
- Toxicological Effects of Technical Xylene Mixtures on the Female Reproductive System: A Systematic Review.Toxics · 2022Review
- An interdisciplinary framework for derivation of occupational exposure limits.Frontiers in public health · 2022Article
- Anemia risk in relation to lead exposure in lead-related manufacturing.BMC public health · 2017Article
- The Scientific Basis of Uncertainty Factors Used in Setting Occupational Exposure Limits.Journal of occupational and environmental hygiene · 2015Article
- Setting Occupational Exposure Limits for Chemical Allergens--Understanding the Challenges.Journal of occupational and environmental hygiene · 2015Article
- Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation.Journal of occupational and environmental hygiene · 2015Article
- Exposure Estimation and Interpretation of Occupational Risk: Enhanced Information for the Occupational Risk Manager.Journal of occupational and environmental hygiene · 2015Article
- State-of-the-Science: The Evolution of Occupational Exposure Limit Derivation and Application.Journal of occupational and environmental hygiene · 2015Article
- The Global Landscape of Occupational Exposure Limits--Implementation of Harmonization Principles to Guide Limit Selection.Journal of occupational and environmental hygiene · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Virtually no occupational exposure standards specify the level of risk for the prescribed exposure, and most occupational exposure limits are not based on quantitative risk assessment (QRA) at all. Wider use of QRA could improve understanding of occupational risks while increasing focus on identifying exposure concentrations conferring acceptably low levels of risk to workers. Exposure-response modeling between a defined hazard and the biological response of interest is necessary to provide a quantitative foundation for risk-based occupational exposure limits; and there has been considerable work devoted to establishing reliable methods quantifying the exposure-response relationship including methods of extrapolation below the observed responses. We review several exposure-response modeling methods available for QRA, and demonstrate their utility with simulated data sets.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.