ArticleSpringerPlus2015
Genomic analysis reveals the biotechnological and industrial potential of levan producing halophilic extremophile, Halomonas smyrnensis AAD6T.
Article in SpringerPlus, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Production and partial characterization of fructose-rich exopolysaccharide from a newly isolated halophilic strain Vreelandella sp. DT-Z4.BMC biotechnology · 2026Article
- Reconstruction and analyses of genome-scaleMetabolic engineering communications · 2024Article
- Metabolic modeling of Halomonas campaniensis improves polyhydroxybutyrate production under nitrogen limitation.Applied microbiology and biotechnology · 2024Article
- Genome-scale metabolic modelling of extremophiles and its applications in astrobiological environments.Environmental microbiology reports · 2024Review
- Strategy for the Adaptation to Stressful Conditions of the Novel Isolated Conditional Piezophilic Strain Halomonas titanicae ANRCS81.Applied and environmental microbiology · 2023Article
- NaCl Concentration-Dependent Aminoglycoside Resistance ofJournal of microbiology and biotechnology · 2021Article
- Genome analysis of a halophilic bacterium Halomonas malpeensis YU-PRIM-29Scientific reports · 2021Article
- Article
- Bacterial biopolymers: from pathogenesis to advanced materials.Nature reviews. Microbiology · 2020Review
- Complete genome sequence of the halophilic PHA-producing bacterium Halomonas sp. SF2003: insights into its biotechnological potential.World journal of microbiology & biotechnology · 2019Article
- Genome analysis of a thermophilic exopolysaccharide-producing bacterium - Geobacillus sp. WSUCF1.Scientific reports · 2019Article
- Insights into metabolic osmoadaptation of the ectoines-producer bacterium Chromohalobacter salexigens through a high-quality genome scale metabolic model.Microbial cell factories · 2018Article
- Microbial Community Structure and Functional Potential Along a Hypersaline Gradient.Frontiers in microbiology · 2018Article
- Osmoregulation in the Halophilic Bacterium Halomonas elongata: A Case Study for Integrative Systems Biology.PloS one · 2017Article
- Systems Biology of Microbial Exopolysaccharides Production.Frontiers in bioengineering and biotechnology · 2015Review
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Authors and funding
7 authors.
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Abstract
Halomonas smyrnensis AAD6T is a gram negative, aerobic, and moderately halophilic bacterium, and is known to produce high levels of levan with many potential uses in foods, feeds, cosmetics, pharmaceutical and chemical industries due to its outstanding properties. Here, the whole-genome analysis was performed to gain more insight about the biological mechanisms, and the whole-genome organization of the bacterium. Industrially crucial genes, including the levansucrase, were detected and the genome-scale metabolic model of H. smyrnensis AAD6T was reconstructed. The bacterium was found to have many potential applications in biotechnology not only being a levan producer, but also because of its capacity to produce Pel exopolysaccharide, polyhydroxyalkanoates, and osmoprotectants. The genomic information presented here will not only provide additional information to enhance our understanding of the genetic and metabolic network of halophilic bacteria, but also accelerate the research on systematical design of engineering strategies for biotechnology applications.
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