Evidence map›Paper›PMID 26251708›Full record

ArticleClinical kidney journal2015

Acute kidney injury associated with androgenic steroids and nutritional supplements in bodybuilders(†).

Safa E Almukhtar, Alaa A Abbas, Dana N Muhealdeen, Michael D Hughson

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Nutritional and Non-Nutritional Strategies in Bodybuilding: Impact on Kidney Function.International journal of environmental research and public health · 2022
    Review
  7. Article
  8. Review
  9. The Use of Dietary Supplements in Fitness Practitioners: A Cross-Sectional Observation Study.International journal of environmental research and public health · 2021
    Observational
  10. Glomerular Filtration Rate and Supraphysiologic-Dose Anabolic-Androgenic Steroid Use: A Cross-sectional Cohort Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Safa E AlmukhtarDepartment of Internal Medicine , Hawler College of Medicine , Erbil (Hawler) , Kurdistan Iraq ; Department of Nephrology , Hawler College of Medicine , Erbil (Hawler) , Kurdistan Iraq.
Alaa A AbbasDepartment of Pathology , Shorsh General Hospital , Sulaimaniyah , Kurdistan Iraq.
Dana N MuhealdeenDepartment of Pathology , Shorsh General Hospital , Sulaimaniyah , Kurdistan Iraq.
Michael D HughsonDepartment of Pathology , Shorsh General Hospital , Sulaimaniyah , Kurdistan Iraq.
Kurdistan Regional Government · IQHawler Medical University · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four bodybuilders who injected anabolic steroids and ingested commercial protein (78-104 g/day) and creatine (15 g/day) products presented with serum creatinine levels between 229.84 and 335.92 µmol/L (2.6-3.8 mg/dL). Renal biopsies revealed acute tubular necrosis. Four weeks after discontinuing injections and supplements, serum creatinine was in the normal range and estimated glomerular filtration rate > 1.00 mL/s (60 mL/min), including two patients with biopsies showing >30% interstitial fibrosis and tubular atrophy. The findings highlight a risk for acute and potentially chronic kidney injury among young men abusing anabolic steroids and using excessive amounts of nutritional supplements.

Indexed as

acute kidney injuryanabolic steroidsbody buildingchronic kidney diseasenutritional supplements

Identifiers

PMID26251708
PMCPMC4515889
OpenAlexW2271868246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.