Evidence map›Paper›PMID 26251697›Full record

ArticleRSC advances

Synthesis of Norbornane Bisether Antibiotics via Silver-mediated Alkylation.

Shane M Hickey, Trent D Ashton, Jonathan M White, Jian Li, Roger L Nation, Heidi Y Yu, Alysha G Elliott, Mark S Butler, Johnny X Huang, Matthew A Cooper and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Defining a lipophilicity window for the antimicrobial activity of 7-Alkoxy-3-Amino coumarin amphiphiles.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  2. Article
  3. Article
  4. Palladium and Iron Cocatalyzed Aerobic Alkene Aminoboration.Journal of the American Chemical Society · 2023
    Article
  5. Short Cationic Peptidomimetic Antimicrobials.Antibiotics (Basel, Switzerland) · 2019
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Shane M HickeyResearch Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Victoria, 3216, Australia.
Trent D AshtonResearch Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Victoria, 3216, Australia.
Jonathan M WhiteBio21 Institute, School of Chemistry, University of Melbourne, Parkville, Victoria, 3010, Australia.
Jian LiDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Science, Royal Parade, Parkville, Victoria, 3052, Australia.
Roger L NationDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Science, Royal Parade, Parkville, Victoria, 3052, Australia.
Heidi Y YuDrug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Science, Royal Parade, Parkville, Victoria, 3052, Australia.
Alysha G ElliottInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.
Mark S ButlerInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.
Johnny X HuangInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.
Matthew A CooperInstitute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.
Frederick M PfefferResearch Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Victoria, 3216, Australia.
Biotechnology Research Center · IRNAACP Legal Defense and Educational Fund · USResearch Institute for Bioscience and Biotechnology · NPUniversity of Queensland · AUUniversity of Melbourne · AU

Funding

Targeting superbugs: discovery and development of new broad-spectrum lipopeptidesR01AI098771 · NIAID · MONASH UNIVERSITY · PI LI, JIAN · 2012 to 2016
$4.3M
NIAID NIH HHS R01 AI098771
6 · The paper itself

Abstract

A small series of norbornane bisether diguanidines have been synthesized and evaluated as antibacterial agents. The key transformation-bisalkylation of norbornane diol

Identifiers

PMID26251697
PMCPMC4523246
OpenAlexW2079310509

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.