Evidence map›Paper›PMID 26251683›Full record

ArticleJournal of clinical medicine research2015

Minimally Symptomatic Atrial Fibrillation Patients Derive Significant Symptom Relief Following Rate Control or Rhythm Control Therapy.

David Ryan King, Neil D Mehta, Anil K Gehi, Irion Pursell, Paul Mounsey, Prabhat Kumar, Ayo Bamimore, Eugene H Chung

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In one paragraph

Article in Journal of clinical medicine research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David Ryan KingUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.
Neil D MehtaUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.
Anil K GehiUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.
Irion PursellUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.
Paul MounseyUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.
Prabhat KumarUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.
Ayo BamimoreUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.
Eugene H ChungUNC Center for Heart and Vascular Care, Department of Medicine, Cardiac Electrophysiology, University of North Carolina at Chapel Hill, NC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt can be challenging to convince asymptomatic to minimally symptomatic patients to pursue treatment of their atrial fibrillation (AF). We hypothesized that once in sinus rhythm, asymptomatic to minimally symptomatic patients would realize they were compensating for moderate symptoms, and that we could quantify this via the Canadian Cardiovascular Society Severity of AF (CCS-SAF) score.

methodsAll patients in our study come from the Symptom Mitigation in Atrial Fibrillation (SMART) study. Upon enrollment all patients were assigned a CCS-SAF score. Patients receiving a CCS-SAF score of 0 or 1 that elected to pursue intervention were contacted by phone and asked about their symptoms post-intervention as compared to pre-intervention. Paired t-test was used for analysis.

resultsOut of 800 patients in the SMART study to date, 48 patients have qualified for our phone survey and presented for follow-up in our clinic. In our cohort, the revised pre-intervention CCS-SAF score was 1.69 ± 1.36 and the post-intervention CCS-SAF score was 0.52 ± 0.80. Thirty-seven patients reported symptom improvement; those who improved were on average 72.4% improved from baseline.

conclusionsWe conclude asymptomatic to minimally symptomatic AF patients benefit from therapy and should be offered intervention despite lack of symptoms.

Indexed as

Antiarrhythmic drugsAtrial fibrillationElectrophysiologyHeart

Identifiers

PMID26251683
PMCPMC4522986

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.