Evidence map›Paper›PMID 26251065›Full record

Trial reportOccupational and environmental medicine2015

Work-focused cognitive-behavioural therapy and individual job support to increase work participation in common mental disorders: a randomised controlled multicentre trial.

Silje Endresen Reme, Astrid Louise Grasdal, Camilla Løvvik, Stein Atle Lie, Simon Øverland

Registry-linked trialOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Occupational and environmental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01146730 (At Work and Coping - Effect Evaluation of Center for Workcoping for Patients With Anxiety and Depression), which is not on this map. Cited by 69 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 7 pooled it
26.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01146730 nacompletednot on this map

At Work and Coping - Effect Evaluation of Center for Workcoping for Patients With Anxiety and Depression

TypeinterventionalSponsorNORCE Norwegian Research Centre ASRan2010 to 2018Enrolled1,202ConditionsAnxiety, DepressionArmsWorkcoping and IPS, Ordinary care by GP or NAV
3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 7 syntheses or guidelines pooled it, 137 citations in OpenAlex.

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  4. Economic analyses of supported employment programmes for people with mental health conditions: A systematic review.European psychiatry : the journal of the Association of European Psychiatrists · 2022
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  6. Interventions to improve return to work in depressed people.The Cochrane database of systematic reviews · 2020
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9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Silje Endresen RemeUni Research Health, Bergen, Norway.
Astrid Louise GrasdalDepartment of Economics, University of Bergen, Bergen, Norway.
Camilla LøvvikUni Research Health, Bergen, Norway Department of Psychosocial Science, University of Bergen, Bergen, Norway.
Stein Atle LieUni Research Health, Bergen, Norway.
Simon ØverlandDepartment of Public Mental Health, Norwegian Institute of Public Health, Bergen, Norway Department of Psychosocial Science, University of Bergen, Bergen, Norway.
Uni Research (Norway) · NONorwegian Institute of Public Health · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCommon mental disorders (CMDs) are a major cause of rising disability benefit expenditures. We urgently need evidence on programmes that can increase work participation in CMDs. The aim of this study was to evaluate the effectiveness of work-focused cognitive-behavioural therapy (CBT) and individual job support for people struggling with work participation due to CMDs.

methodsA randomised controlled multicentre trial (RCT) including 1193 participants was conducted. Participants were on sick leave, at risk of going on sick leave or on long-term benefits. The intervention integrated work-focused CBT with individual job support. The control group received usual care. The main outcome was objectively ascertained work participation at 12 months follow-up, with changes in mental health and health-related quality of life as secondary outcomes.

resultsA larger proportion of participants in the intervention group had increased or maintained their work participation at follow-up compared to the control group (44.2% vs 37.2%, p=0.015). The difference remained significant after 18 months (difference 7.8%, p=0.018), and was even stronger for those on long-term benefits (difference 12.2%, p=0.007). The intervention also reduced depression (t=3.23, p≤0.001) and anxiety symptoms (t=2.52, p=0.012) and increased health-related quality of life (t=2.24, p=0.026) more than usual care.

conclusionsA work-focused CBT and individual job support was more effective than usual care in increasing or maintaining work participation for people with CMDs. The effects were profound for people on long-term benefits. This is the first large-scale RCT to demonstrate an effect of a behavioural intervention on work participation for the large group of workers with CMDs. TRIAL REGISTRATION NUMBER: ClinicalTrials.gov, registration number: NCT01146730.

Indexed as

AdultAge FactorsCognitive Behavioral TherapyEmployment, SupportedFemaleHumansLogistic ModelsMaleMental DisordersMiddle AgedMultivariate AnalysisNorwayProgram EvaluationRisk AssessmentSex FactorsSick Leave

Identifiers

PMID26251065
PMCPMC4602235
OpenAlexW2167890993

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.