Evidence map›Paper›PMID 26251064›Full record

ArticleOccupational and environmental medicine2015

Work schedule and physical factors in relation to fecundity in nurses.

Audrey J Gaskins, Janet W Rich-Edwards, Christina C Lawson, Eva S Schernhammer, Stacey A Missmer, Jorge E Chavarro

Abstract read
PubMed Full text at PMC Publisher
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Article in Occupational and environmental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 160 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Audrey J GaskinsDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Janet W Rich-EdwardsDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA Department of Medicine, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Christina C LawsonNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Cincinnati, Ohio, USA.
Eva S SchernhammerDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Stacey A MissmerDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Jorge E ChavarroDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Harvard University · USCenters for Disease Control and Prevention · US

Funding

TRAINING GRANT IN ACADEMIC NUTRITIONT32DK007703 · NIDDK · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI CHRISTOPHER P DUGGAN, Frank B Hu · 1994 to 2026
$7.8M
Predoctoral Training Program in Reproductive, Perinatal & Pediatric EpidemiologyT32HD060454 · NICHD · HARVARD SCHOOL OF PUBLIC HEALTH · PI MICHELS, KARIN B · 2010 to 2014
$1.1M
Intramural CDC HHS CC999999NICHD NIH HHS T32 HD060454NICHD NIH HHS T32HD060454NIDDK NIH HHS T32 DK007703NIDDK NIH HHS T32DK007703PHS HHS 200-2013-M-54978
6 · The paper itself

Abstract

objectivesTo evaluate the association of work schedule and physical factors with fecundity.

methodsWomen currently employed outside the home and trying to get pregnant (n=1739) in the Nurses' Health Study 3 cohort (2010-2014) were included in this analysis. Work schedule and physical labour were self-reported on the baseline questionnaire, and every 6 months thereafter the women reported the duration of their ongoing pregnancy attempt. Multivariable accelerated failure time models were used to estimate time ratios (TR) and 95% CIs.

resultsAmong the 1739 women (median age=33 years, 93% Caucasian) the estimated proportions of women not pregnant after 12 and 24 months were 16% and 5%, respectively. None of the various shift work patterns were associated with duration of pregnancy attempt (as a surrogate for fecundity). However, women working >40 h/week had a 20% (95% CI 7 to 35%) longer median duration of pregnancy attempt compared to women working 21-40 h/week (p-trend=0.005). Women whose work entailed heavy lifting or moving (ie, 25+ pounds) >15 times/day also had a longer median duration of pregnancy attempt (adjusted TR=1.49; 95% CI 1.20 to 1.85) compared to women who never lifted or moved heavy loads (p-trend=0.002). The association between heavy moving and lifting and duration of pregnancy attempt was more pronounced among overweight or obese women (body mass index, BMI<25: TR=1.17; 95% CI 0.88 to 1.56; BMI≥25: TR=2.03, 95% CI 1.48 to 2.79; p-interaction=0.007).

conclusionsWorking greater than 40 h per week and greater frequency of lifting or moving a heavy load were associated with reduced fecundity in a cohort of nurses planning pregnancy.

Indexed as

FertilityNursesWorkWork Schedule ToleranceAdultBody Mass IndexFemaleHumansInfertility, FemaleLiftingObesityOccupational ExposurePregnancySurveys and QuestionnairesFertility < Methodology, specialityPhysical work < Materials, exposures and occupational groups

Identifiers

PMID26251064
PMCPMC4609294
OpenAlexW1898733479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.