Evidence map›Paper›PMID 26251048›Full record

Trial reportClinical infectious diseases : an official publication of the Infectious Diseases Society of America2015

HIV care continuum among men who have sex with men and persons who inject drugs in India: barriers to successful engagement.

Shruti H Mehta, Gregory M Lucas, Suniti Solomon, Aylur K Srikrishnan, Allison M McFall, Neeraj Dhingra, Paneerselvam Nandagopal, M Suresh Kumar, David D Celentano, Sunil S Solomon

Registry-linked trialOpen access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01686750 (A Cluster Randomized Trial of Integrated Care Centers to Improve Access to HIV Prevention, Testing, and Treatment Services Among High-Risk Vulnerable Populations in India), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01686750 nacompletednot on this map

A Cluster Randomized Trial of Integrated Care Centers to Improve Access to HIV Prevention, Testing, and Treatment Services Among High-Risk Vulnerable Populations in India

TypeinterventionalSponsorJohns Hopkins UniversityRan2012 to 2017Enrolled21,726ConditionsHIV InfectionArmsIntegrated care centers
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Barriers and facilitators to primary care engagement for people who inject drugs: A systematic review.Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Shruti H MehtaDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health.
Gregory M LucasDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Suniti SolomonY.R. Gaitonde Centre for AIDS Research and Education, Chennai, Tamil Nadu.
Aylur K SrikrishnanY.R. Gaitonde Centre for AIDS Research and Education, Chennai, Tamil Nadu.
Allison M McFallDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health.
Neeraj DhingraNational AIDS Control Organisation, New Delhi, India.
Paneerselvam NandagopalY.R. Gaitonde Centre for AIDS Research and Education, Chennai, Tamil Nadu.
M Suresh KumarY.R. Gaitonde Centre for AIDS Research and Education, Chennai, Tamil Nadu.
David D CelentanoDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health.
Sunil S SolomonDepartment of Epidemiology, Johns Hopkins University Bloomberg School of Public Health Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland Y.R. Gaitonde Centre for AIDS Research and Education, Chennai, Tamil Nadu.
Johns Hopkins University · USYR Gaitonde Centre for AIDS Research and Education · INJohns Hopkins Medicine · USNational AIDS Control Organisation · IN

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
Integrated Care Clinics for IDUs in India: a cluster randomized trialR01DA032059 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M, MEHTA, SHRUTI H · 2011 to 2015
$6.3M
Preventing HIV Infection Among MSM in Southern IndiaR01MH089266 · NIMH · JOHNS HOPKINS UNIVERSITY · PI CELENTANO, DAVID D. · 2010 to 2015
$2.9M
Treatment outcomes and comorbidity in HIV-infected IDUK24DA035684 · NIDA · JOHNS HOPKINS UNIVERSITY · PI LUCAS, GREGORY M · 2014 to 2024
$1.5M
NIAID NIH HHS P30 AI094189NIDA NIH HHS DA 032059NIDA NIH HHS K24 DA035684NIDA NIH HHS R01 DA032059NIMH NIH HHS MH 89266NIMH NIH HHS R01 MH089266
6 · The paper itself

Abstract

backgroundWe characterize the human immunodeficiency virus (HIV) care continuum for men who have sex with men (MSM) and persons who inject drugs (PWID) across India.

methodsWe recruited 12 022 MSM and 14 481 PWID across 26 Indian cities, using respondent-driven sampling (September 2012 to December 2013). Participants were aged ≥18 years and either self-identified as male and reported sex with a man in the prior year (MSM) or reported injection drug use in the prior 2 years (PWID). Correlates of awareness of HIV-positive status were characterized using multilevel logistic regression.

resultsA total of 1146 MSM were HIV infected, of whom a median of 30% were aware of their HIV-positive status, 23% were linked to care, 22% were retained before antiretroviral therapy (ART), 16% had started ART, 16% were currently receiving ART, and 10% had suppressed viral loads. There was site variability (awareness range, 0%-90%; suppressed viral load range, 0%-58%). A total of 2906 PWID were HIV infected, of whom a median of 41% were aware, 36% were linked to care, 31% were retained before ART, 20% had started ART, 18% were currently receiving ART, and 15% had suppressed viral loads. Similar site variability was observed (awareness range: 2%-93%; suppressed viral load range: 0%-47%). Factors significantly associated with awareness were region, older age, being married (MSM) or female (PWID), use of other services (PWID), more lifetime sexual partners (MSM), and needle sharing (PWID). Ongoing injection drug use (PWID) and alcohol use (MSM) were associated with lower awareness.

conclusionsIn this large sample, the major barrier to HIV care engagement was awareness of HIV-positive status. Efforts should focus on linking HIV testing to other essential services. CLINICAL TRIALS REGISTRATION: NCT01686750.

Indexed as

Continuity of Patient CareHomosexuality, MaleAdultFemaleHIV InfectionsHumansIndiaMaleNeedle SharingRisk FactorsRisk-TakingSexual PartnersSubstance Abuse, IntravenousHIV care continuumIndiamen who have sex with menpeople who inject drugs

Identifiers

PMID26251048
PMCPMC4643485
OpenAlexW2170579067

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.