Evidence map›Paper›PMID 26250921›Full record

ReviewClinics in perinatology2015

Platelet Transfusions in the Neonatal Intensive Care Unit.

Katherine Sparger, Emoke Deschmann, Martha Sola-Visner

Abstract readReview
In one paragraph

Review in Clinics in perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Review
  5. Platelets in the neonate: Not just a small adult.Research and practice in thrombosis and haemostasis · 2022
    Article
  6. Article
  7. Neonatal coagulopathies: A review of established and emerging treatments.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  8. Article
  9. Observational
  10. Article
  11. Ontogeny of platelet function.Blood advances · 2019
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katherine SpargerDepartment of Pediatrics, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
Emoke DeschmannDepartment of Neonatology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Martha Sola-VisnerDivision of Newborn Medicine, Boston Children's Hospital, Enders Research Building, Room 961, 300 Longwood Avenue, Boston, MA 02115, USA. Electronic address: Martha.Sola-Visner@childrens.harvard.edu.

Funding

THE RoLE OF NEONATAL ANEMIA IN LEARNING AND MEMORYP01HL046925 · NHLBI · UNIVERSITY OF IOWA · PI JOSEPHSON, CASSANDRA D · 1992 to 2022
$34.3M
Platelet Transfusions in the Neonatal Intensive Care UnitR21HL087150 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI SOLA-VISNER, MARTHA C. · 2007 to 2008
$331k
NHLBI NIH HHS P01 HL046925NHLBI NIH HHS R21 HL087150
6 · The paper itself

Abstract

There is significant world-wide variability in platelet transfusion thresholds used to transfuse thrombocytopenic neonates. A large multicenter randomized controlled trial comparing 2 different platelet transfusion thresholds in neonates is currently ongoing, and should provide data to guide transfusion practice. However, several studies have found that factors other than the degree of thrombocytopenia determine the bleeding risk. Thus, it will be important to develop better tests to assess primary hemostasis and bleeding risk in neonates.

Indexed as

Intensive Care Units, NeonatalHumansInfant, NewbornPlatelet TransfusionThrombocytopeniaNeonatal intensive care unitPlatelet transfusionsThrombocytopenia

Identifiers

PMID26250921
PMCPMC4535179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.