Evidence map›Paper›PMID 26250917›Full record

ReviewClinics in perinatology2015

Darbepoetin Administration in Term and Preterm Neonates.

Shrena Patel, Robin K Ohls

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Neonatal subgaleal hemorrhage: twenty years of trends in incidence, associations, and outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
  7. Review
  8. Emerging therapies and management for neonatal encephalopathy-controversies and current approaches.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Shrena PatelDivision of Neonatology, Department of Pediatrics, University of Utah, 296 Chipeta Way, Salt Lake City, UT 84105, USA.
Robin K OhlsDivision of Neonatology, Department of Pediatrics, University of New Mexico, MSC10 5590, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA. Electronic address: rohls@salud.unm.edu.
University of New Mexico · USUniversity of Utah · US

Funding

Brain imaging and developmental follow-up of infants treated with erythropoietinR01HD059856 · NICHD · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI OHLS, ROBIN K · 2010 to 2014
$2.2M
NICHD NIH HHS R01 HD059856NICHD NIH HHS R01HD059856
6 · The paper itself

Abstract

Erythropoiesis-stimulating agents (ESAs) such as erythropoietin have been studied as red cell growth factors in preterm and term infants for more than 20 years. Recent studies have evaluated darbepoetin (Darbe, a long-acting ESA) for both erythropoietic effects and potential neuroprotection. We review clinical trials of Darbe in term and preterm infants, which have reported significant erythropoietic uses and neuroprotective effects. ESAs show great promise in decreasing or eliminating transfusions, and in preventing and treating brain injury in term and preterm infants.

Indexed as

Darbepoetin alfaDrug Administration ScheduleHematinicsHumansInfant, NewbornInfant, PrematureInfant, Premature, DiseasesNeuroprotectionTreatment OutcomeDarbepoetin alfaHematinicsAnemiaDarbepoetinErythropoiesis-stimulating agentsNeurodevelopmentNeuroprotectionTransfusions

Identifiers

PMID26250917
PMCPMC4529960
OpenAlexW1496335414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.