Evidence map›Paper›PMID 26250695›Full record

ReviewMedical science monitor basic research2015

Continuous-Flow Left Ventricular Assist Device Thrombosis: A Danger Foreseen is a Danger Avoided.

Javid Fatullayev, Mostafa Samak, Anton Sabashnikov, Mohamed Zeriouh, Parwis B Rahmanian, Yeong-Hoon Choi, Bastian Schmack, Klaus Kallenbach, Arjang Ruhparwar, Kaveh Eghbalzadeh and 7 more

Abstract readReview
In one paragraph

Review in Medical science monitor basic research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Recent Developments in Ventricular Assist Device Therapy.Reviews in cardiovascular medicine · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Small Left Ventricular Size Is an Independent Risk Factor for Ventricular Assist Device Thrombosis.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2019
    Article
  14. Effects of Cone-Shaped Bend Inlet Cannulas of an Axial Blood Pump on Thrombus Formation: An Experiment and Simulation Study.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  15. Article
  16. Effect of Different Rotational Directions of BJUT-II VAD on Aortic Swirling Flow Characteristics: A Primary Computational Fluid Dynamics Study.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Javid FatullayevDepartment of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, London, United Kingdom.
Mostafa SamakDepartment of Cardiothoracic Surgery, University Hospital of Cologne, Cologne, Germany.
Anton SabashnikovDepartment of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, London, United Kingdom.
Mohamed ZeriouhDepartment of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, London, United Kingdom.
Parwis B RahmanianDepartment of Cardiothoracic Surgery, Heart Center, University Hospital Cologne, Cologne, Germany.
Yeong-Hoon ChoiDepartment of Cardiothoracic Surgery, Heart Center, University Hospital Cologne, Cologne, Germany.
Bastian SchmackDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany.
Klaus KallenbachDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany.
Arjang RuhparwarDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany.
Kaveh EghbalzadehDepartment of Cardiothoracic Surgery, Heart Center, University Hospital Cologne, Cologne, Germany.
Pascal M DohmenDepartment of Cardiovascular Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Matthias KarckDepartment of Cardiac Surgery, Heart and Marfan Center, University of Heidelberg, Heidelberg, Germany.
Jens WippermannDepartment of Cardiothoracic Surgery, Heart Center, University Hospital Cologne, Cologne, Germany.
Thorsten WahlersDepartment of Cardiothoracic Surgery, Heart Center, University Hospital Cologne, Cologne, Germany.
Aron-Frederik PopovDepartment of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, London, United Kingdom.
Andre R SimonDepartment of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, London, United Kingdom.
Alexander WeymannDepartment of Cardiothoracic Transplantation & Mechanical Circulatory Support, Royal Brompton and Harefield NHS Foundation Trust, Harefield, Middlesex, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left ventricular assist devices (LVAD) are an increasingly implemented therapeutic intervention for patients with end-stage heart failure. A growing body of evidence, however, has shown an elevated risk of device thrombosis, a major complication jeopardizing the patient's post-implantation survival. To date, multiple causative factors for LVAD thrombosis have been identified, such as internal shear stress, device material, infection, and inadequate anticoagulation. Understanding the mechanisms leading to LVAD thrombosis will not only enable device optimization, but also allow for better patient handling, hence improving post-implantation outcome. In this review we highlight the most commonly identified factors leading to LVAD thrombosis and discuss their mechanisms.

Indexed as

Heart-Assist DevicesCoronary DiseaseCoronary ThrombosisHumansVentricular Function, Left

Identifiers

PMID26250695
PMCPMC4500598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.