Evidence map›Paper›PMID 26250613›Full record

ArticleOrthodontics & craniofacial research2015

Growth characteristics underlying the lack of a chin in pigs: a histomorphometric study.

J Price, B C Tee, K Vig, S Shanker, K Kennedy, Z Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Orthodontics & craniofacial research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J PriceDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
B C TeeDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
K VigDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
S ShankerDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
K KennedyDivision of Oral and Maxillofacial Surgery, College of Dentistry, The Ohio State University, Columbus, OH, USA.
Z SunDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.

Funding

Single-tooth extraction site bone loss ---- functional disuse or overuse?R03DE019817 · NIDCR · OHIO STATE UNIVERSITY · PI SUN, ZONGYANG · 2010 to 2011
$229k
NIDCR NIH HHS DE019817NIDCR NIH HHS R03 DE019817
6 · The paper itself

Abstract

objectivesDespite similar mandibular growth to that of humans, pigs lack a chin projection as shown in most humans. To understand whether this divergence is contributed to differences in local symphyseal growth, this project characterized bone modeling activities at the symphyseal surfaces of juvenile pigs. MATERIAL AND

methodsSymphyseal specimens from two age groups (4- and 6-month-old, n = 10) were processed into histological sections with and without decalcification, which were assessed for surface mineral apposition and bone resorption, respectively. In a blinded fashion, measurements of four parameters (MAR: mineral apposition rate, MAZ: mineral apposition zone, ES/BS: eroded surface and OC.N/BS: osteoclast number) were obtained and tested by a multivariate two-way mixed-model analyses of variance (manova) for the differences between symphyseal regions and ages.

resultsQualitatively, pig symphyseal labial and lingual surfaces were horizontally oriented and characterized by mineral apposition and bone resorption, respectively. Quantitatively, labial mineral apposition tended to be greater rostrally than caudally at 4 months, which became greater caudally than rostrally at 6 months (region/age interactions: p = 0.127 for MAR, p = 0.012 for MAZ). Lingual bone resorption tended to be greater caudally than rostrally, but only ES/BS measurements were significant (p = 0.039) regardless of age, while OC.N/BS measurements varied with ages and regions (age/region interaction, p = 0.087).

conclusionsInsufficient differential in symphyseal surface modeling between the labial-caudal and labial-rostral regions contributes to the lack of chin projection in the pig.

Indexed as

Age FactorsAnimalsBone RemodelingBone ResorptionCalcification, PhysiologicCell CountChinFemaleFluorescent DyesImage Processing, Computer-AssistedMandibleModels, AnimalOsteoclastsOsteogenesisSwineFluorescent Dyesbone formationchinhistologyosteogenesisSus scrofa

Identifiers

PMID26250613
PMCPMC4639918

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.