ArticleDeutsches Arzteblatt international2015
Transfusion of Packed Red Cells: Indications, Triggers and Adverse Events.
Article in Deutsches Arzteblatt international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Positive impact of retrograde autologous priming in adult patients undergoing cardiac surgery: a randomized clinical trial.Journal of cardiothoracic surgery · 2018Trial
- AI and Blood Banking: Predicting Transfusion Demand - A Systematic Review of Forecasting Approaches.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026Review
- Hematocrit and total protein elimination as quality control parameters of cell salvage.The journal of extra-corporeal technology · 2025Article
- Oral and Intravenous Iron Therapy.Advances in experimental medicine and biology · 2025Review
- Article
- From Unit to Dose: A Machine Learning Approach for Precise Prediction of Hemoglobin and Iron Content in Individual Packed Red Blood Cell Units.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Predictors for blood loss and transfusion frequency to guide blood saving programs in primary knee- and hip-arthroplasty.Scientific reports · 2021Article
- The association of disease type, pre-transplant hemoglobin level and platelet count with transfusion requirement after autologous hematopoietic stem cell transplantation.Caspian journal of internal medicine · 2021Article
- [A critical carol : Being an essay on anemia, suffocation, starvation, and other forms of intensive care, after the manner of Dickens].Der Anaesthesist · 2020Review
- Gender differences in blood transfusion strategy for patients with hip fractures - a retrospective analysis.International journal of medical sciences · 2020Observational
- [Patient blood management : Medical concept for increasing patient safety].Der Anaesthesist · 2020Review
- Anemia and red blood cell transfusion practice in prolonged mechanically ventilated patients admitted to a specialized weaning center: an observational study.BMC pulmonary medicine · 2019Observational
- [Overtreatment in intensive care medicine].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2019Review
- Hemolysis risk after packed red blood cells transfusion with infusion pumps.Revista latino-americana de enfermagem · 2018Article
- Risk perception of blood transfusions - a comparison of patients and allied healthcare professionals.BMC health services research · 2018Article
- Demographic characteristics of blood and blood components transfusion recipients and pattern of blood utilization in a tertiary health institution in southern Nigeria.BMC hematology · 2018Article
- [The old man and the I sea U : Essay on faith, fate and evidence - after the manner of Hemingway].Der Anaesthesist · 2017Article
- Article
- [Perioperative management of transthoracic oesophagectomies : Fundamentals of interdisciplinary care and new approaches to accelerated recovery after surgery].Der Anaesthesist · 2016Review
- Creating blood conservation for a cardiothoracic surgical hospital: when you have to start from scratch!Cardiovascular journal of AfricaArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAbout four million units of packed red cells are transfused in Germany every year. The safety of blood transfusions is further improved by modern production methods and molecular diagnostic techniques.
methodsThis review is based on selected publications,including the German guidelines and regulations and the German Transfusion Act.
resultsPacked red blood cells are transfused to prevent tissue hypoxia. As the clinical manifestations of anemia are nonspecific, the indication for transfusion is based on surrogate parameters, such as the hemoglobin (Hb) concentration, in addition to clinical criteria. For patients with unimpaired cardiopulmonary and vascular function, transfusion is generally indicated at hemoglobin values of 6 g/dL (3.7 mmol/L) or less. Randomized controlled trials have shown that a restrictive transfusion strategy (trigger: Hb 7-8 g/dL) in certain patient groups is as effective as a more liberal strategy (trigger: Hb about 10 g/dL). The most frequent causes for transfusion errors are lack of informed consent, lack of identity checking and/or AB0 identity testing, and the drawing of blood samples in unlabelled tubes.
conclusionOvertransfusion, undertransfusion, as well as other transfusion errors can be markedly reduced by means of appropriate organizational measures and training.
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