ArticleG3 (Bethesda, Md.)2015
Genome-Wide Linkage Analysis Identifies Loci for Physical Appearance Traits in Chickens.
Article in G3 (Bethesda, Md.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- A ∼18 kb upstream deletion of H2AFY is associated with the feathered leg trait in Yanying chickens.Poultry science · 2026Article
- A review of genetic variation underlying chicken phenotypic diversity.Poultry science · 2025Review
- Integrating whole-genome re-sequencing and transcriptome data to reveal the molecular mechanism of TBX5 gene regulating feathered feet in Guangxi native chickens.Poultry science · 2025Article
- Genome-Wide Association Study on Body Conformation Traits in Xinjiang Brown Cattle.International journal of molecular sciences · 2024Article
- New findings on the genetic basis of feathered legs in chickens: association of CUBN gene mutations with feathered-leg phenotype.Journal of animal science · 2024Article
- Genetic markers associated with bone composition in Rhode Island Red laying hens.Genetics, selection, evolution : GSE · 2023Article
- Genomic and gene expression associations to morphology of a sexual ornament in the chicken.G3 (Bethesda, Md.) · 2022Article
- Phenotypic Analysis of Growth and Morphological Traits in Miniature Breeds of Japanese Indigenous Chickens.The journal of poultry science · 2022Article
- Genome-wide detection of CNVs and their association with performance traits in broilers.BMC genomics · 2021Article
- Mutations Upstream of the TBX5 and PITX1 Transcription Factor Genes Are Associated with Feathered Legs in the Domestic Chicken.Molecular biology and evolution · 2020Article
- Parallel Genetic Origin of Foot Feathering in Birds.Molecular biology and evolution · 2020Article
- Genome-wide association studies targeting the yield of extraembryonic fluid and production traits in Russian White chickens.BMC genomics · 2019Article
- Genome-wide association study of body weight in Wenshang Barred chicken based on the SLAF-seq technology.Journal of applied genetics · 2018Review
- Genomic determinants of epidermal appendage patterning and structure in domestic birds.Developmental biology · 2017Article
- A Complex Structural Variation on Chromosome 27 Leads to the Ectopic Expression of HOXB8 and the Muffs and Beard Phenotype in Chickens.PLoS genetics · 2016Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physical appearance traits, such as feather-crested head, comb size and type, beard, wattles size, and feathered feet, are used to distinguish between breeds of chicken and also may be associated with economic traits. In this study, a genome-wide linkage analysis was used to identify candidate regions and genes for physical appearance traits and to potentially provide further knowledge of the molecular mechanisms that underlie these traits. The linkage analysis was conducted with an F2 population derived from Beijing-You chickens and a commercial broiler line. Single-nucleotide polymorphisms were analyzed using the Illumina 60K Chicken SNP Beadchip. The data were used to map quantitative trait loci and genes for six physical appearance traits. A 10-cM/0.51-Mb region (0.0-10.0 cM/0.00-0.51 Mb) with 1% genome-wide significant level on LGE22C19W28_E50C23 linkage group (LGE22) for crest trait was identified, which is likely very closely linked to the HOXC8. A QTL with 5% chromosome-wide significant level for comb weight, which partly overlaps with a region identified in a previous study, was identified at 74 cM/25.55 Mb on chicken (Gallus gallus; GG) chromosome 3 (i.e., GGA3). For beard and wattles traits, an identical region 11 cM/2.23 Mb (0.0-11.0 cM/0.00-2.23 Mb) including WNT3 and GH genes on GGA27 was identified. Two QTL with 1% genome-wide significant level for feathered feet trait, one 9-cM/2.80-Mb (48.0-57.0/13.40-16.20 Mb) region on GGA13, and another 12-cM/1.45-Mb (41.0-53.0 cM/11.37-12.82 Mb) region on GGA15 were identified. These candidate regions and genes provide important genetic information for the physical appearance traits in chicken.
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