Evidence map›Paper›PMID 26247955›Full record

ReviewViruses2015

Papillomavirus Infectious Pathways: A Comparison of Systems.

Jennifer Biryukov, Craig Meyers

Abstract readReview
In one paragraph

Review in Viruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. 3D Tissue Culture Model for Virology Studies.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Activity ofInternational journal of molecular sciences · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Papillomaviruses Go Retro.Pathogens (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jennifer BiryukovDepartment of Microbiology and Immunology, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA. jhopkins@hmc.psu.edu.
Craig MeyersDepartment of Microbiology and Immunology, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA. cmm10@psu.edu.

Funding

Mechanistic Investigations of Ethnic Differences in HPV VariantsU01CA179724 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MEYERS, CRAIG M · 2013 to 2017
$1.5M
Genetic Analysis of Papillomavirus Virion MorphogenesisR01AI057988 · NIAID · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MEYERS, CRAIG M · 2006 to 2009
$1.4M
NCI NIH HHS U01 CA179724NCI NIH HHS U01CA179724-02NIAID NIH HHS R01 AI057988NIAID NIH HHS R01AI57988
6 · The paper itself

Abstract

The HPV viral lifecycle is tightly linked to the host cell differentiation, causing difficulty in growing virions in culture. A system that bypasses the need for differentiating epithelium has allowed for generation of recombinant particles, such as virus-like particles (VLPs), pseudovirions (PsV), and quasivirions (QV). Much of the research looking at the HPV life cycle, infectivity, and structure has been generated utilizing recombinant particles. While recombinant particles have proven to be invaluable, allowing for a rapid progression of the HPV field, there are some significant differences between recombinant particles and native virions and very few comparative studies using native virions to confirm results are done. This review serves to address the conflicting data in the HPV field regarding native virions and recombinant particles.

Indexed as

HumansPapillomaviridaePapillomavirus InfectionsRecombination, GeneticVirionVirologyVirus Cultivationhuman papillomavirus (HPV)native virions (NV)pseudovirions (PsV)quasivirions (QV)virusvirus-like particles (VLPs)

Identifiers

PMID26247955
PMCPMC4576184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.