Evidence map›Paper›PMID 26247895›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2015

Understanding HIV Care Provider Attitudes Regarding Intentions to Prescribe PrEP.

Amanda D Castel, Daniel J Feaster, Wenze Tang, Sarah Willis, Heather Jordan, Kira Villamizar, Michael Kharfen, Michael A Kolber, Allan Rodriguez, Lisa R Metsch

Registry-linked trialAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03617874 (PC4PrEP), which is not on this map. Cited by 53 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 3 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03617874 nacompletednot on this mapstarted 2020, after this paper: background citation

PC4PrEP: Integrating Pre-Exposure Prophylaxis (PrEP) Into Primary Care

TypeinterventionalSponsorAlbert Einstein College of MedicineRan2020 to 2022Enrolled22ConditionsHuman Immunodeficiency Virus TransmissionArmsPC4PrEP- Intervention Clinics, Standard of Care Clinics
3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Health Care Providers' Reported Barriers to Pre-Exposure Prophylaxis Initiation Among Cisgender Women.Health education & behavior : the official publication of the Society for Public Health Education · 2026
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  9. Knowledge and attitudes of HIV pre-exposure prophylaxis among nurses in South Africa.African journal of primary health care & family medicine · 2023
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  17. Financing and Delivering Pre-Exposure Prophylaxis (PrEP) to End the HIV Epidemic.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Amanda D Castel*Department of Epidemiology and Biostatistics, The Milken Institute School of Public Health, George Washington University, Washington, DC; †Biostatistics Division, Department of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL; ‡Florida Department of Health, Miami-Dade County, Miami, FL; §District of Columbia Department of Health, HIV/AIDS, Hepatitis, STD, TB Administration, Washington, DC; ‖Department of Medicine, University of Miami Miller School of Medicine, Miami, FL; and ¶Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY.
Daniel J Feaster
Wenze Tang
Sarah Willis
Heather Jordan
Kira Villamizar
Michael Kharfen
Michael A Kolber
Allan Rodriguez
Lisa R Metsch
Milken Institute · USUniversity of Miami · USColumbia University · USGovernment of the District of Columbia · USMiami Dade College · US

Funding

The Florida Node Alliance of the National Drug Abuse Treatment Clinical Trials NetworkUG1DA013720 · NIDA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Daniel J Feaster, Viviana Elizabeth Horigian · 2015 to 2026
$50.6M
The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MILTON L WAINBERG · 2003 to 2026
$48.2M
University of Miami Developmental Center for AIDS Research (D-CFAR)P30AI073961 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALLAN E RODRIGUEZ · 2007 to 2026
$33.8M
The District of Columbia Developmental Center for AIDS Research (DC D-CFAR)P30AI087714 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI GREENBERG, ALAN EDWARD · 2010 to 2014
$8.4M
NIAID NIH HHS P30 AI073961NIAID NIH HHS P30AI073961NIAID NIH HHS P30 AI087714NIDA NIH HHS UG1 DA013720NIMH NIH HHS P30 MH043520PHS HHS P0HC-2006-C-0030PHS HHS P30A1073961
6 · The paper itself

Abstract

introductionPreexposure prophylaxis (PrEP) is a promising approach to reducing HIV incidence. So, garnering the support of HIV providers, who are most familiar with antiretrovirals and likely to encounter patients in HIV serodiscordant relationships, to scale-up PrEP implementation is essential. We sought to determine whether certain subgroups of HIV providers were more likely to intend to prescribe PrEP.

methodsSurveys were administered to HIV providers in Miami, Florida and Washington, District of Columbia. Composite scores were developed to measure PrEP knowledge, experience, and likelihood of prescribing. Latent class analysis was used to stratify provider attitudes toward PrEP.

resultsAmong 142 HIV providers, 73.2% had cared for more than 20 HIV-infected patients in the previous 3 months; 17% had ever prescribed PrEP. Latent class analysis identified 2 classes of providers (entropy, 0.904); class 1 (n = 95) found PrEP less effective and perceived barriers to prescribing it; class 2 (n = 47) perceived PrEP as moderately effective and perceived fewer barriers to prescribing it. Compared with class 2, class 1 had significantly less experience with PrEP delivery (t(22.7) = 2.88, P = 0.009) and was significantly less likely to intend to prescribe to patients with multiple sex partners (20% vs. 43%, P = 0.04) and those with a drug use history (7% vs. 24%, P = 0.001).

conclusionsAlthough most HIV providers found PrEP to be effective, those considering it less effective had limited knowledge and experience with PrEP and had lesser intentions to prescribe. Provider training regarding whom should receive PrEP and addressing potential barriers to PrEP provision are needed if this HIV prevention method is to be optimized.

Indexed as

Attitude of Health PersonnelPre-Exposure ProphylaxisAdultAnti-HIV AgentsDrug PrescriptionsFemaleHIV InfectionsHumansMaleMiddle AgedPractice Patterns, Physicians'Anti-HIV Agents

Identifiers

PMID26247895
PMCPMC4644475
OpenAlexW1410703977

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.