Evidence map›Paper›PMID 26247638›Full record

ArticleJournal of occupational and environmental medicine2015

Longitudinal Assessment of Blood Cholinesterase Activities Over 2 Consecutive Years Among Latino Nonfarmworkers and Pesticide-Exposed Farmworkers in North Carolina.

Sara A Quandt, Carey N Pope, Haiying Chen, Phillip Summers, Thomas A Arcury

Abstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pesticide exposure among Latinx child farmworkers in North Carolina.American journal of industrial medicine · 2021
    Article
  6. Article
  7. Review
  8. Acetylcholinesterase activity and time after a peak pesticide-use period among Ecuadorian children.International archives of occupational and environmental health · 2018
    Article
  9. Article
  10. Article
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  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sara A QuandtFrom the Department of Epidemiology and Prevention (Dr Quandt), Department of Biostatistical Sciences (Dr Chen), and Department of Family and Community Medicine (Mr Summers and Dr Arcury), Wake Forest School of Medicine, Winston-Salem, NC; and Department of Physiological Sciences (Dr Pope), Center for Veterinary Sciences, Oklahoma State University, Stillwater.
Carey N Pope
Haiying Chen
Phillip Summers
Thomas A Arcury
Stillwater (Canada) · CA

Funding

The Effect of Pesticide Exposure on Cognitive and Brain Development in Latino Children: PACE5 Administrative Supplement 2R01ES008739 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARCURY, THOMAS A., LAURIENTI, PAUL · 2000 to 2022
$11.1M
NIEHS NIH HHS R01 ES008739NIEHS NIH HHS R01-ES008739
6 · The paper itself

Abstract

objectiveThis study (1) describes patterns of whole blood total cholinesterase, acetylcholinesterase, and butyrylcholinesterase activities across the agricultural season, comparing farmworkers and nonfarmworkers; and (2) explores differences between farmworkers' and non-farmworkers' likelihood of cholinesterase depression.

methodsBlood samples from 210 Latino male farmworkers and 163 Latino workers with no occupational pesticide exposure collected 8 times across 2 agricultural seasons were analyzed. Mean cholinesterase activity levels and depressions 15% or more were compared by month.

resultsFarmworkers had significantly lower total cholinesterase and butyrylcholinesterase activities in July and August and lower acetylcholinesterase activity in August. Farmworkers had significantly greater likelihood of cholinesterase depression for each cholinesterase measure across the agricultural season. SIGNIFICANCE: A repeated-measures design across 2 years with a nonexposed control group demonstrated anticholinesterase effects in farmworkers. Current regulations designed to prevent pesticide exposure are not effective.

Indexed as

Hispanic or LatinoAcetylcholinesteraseAdultAgricultural Workers' DiseasesButyrylcholinesteraseCarbamatesCase-Control StudiesCholinesterasesHumansLongitudinal StudiesMaleNorth CarolinaOccupational ExposureOrganophosphorus CompoundsPesticidesReference ValuesAcetylcholinesteraseButyrylcholinesteraseCarbamatesCholinesterasesOrganophosphorus CompoundsPesticides

Identifiers

PMID26247638
PMCPMC4530499
OpenAlexW1085159448

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.