Evidence map›Paper›PMID 26246986›Full record

ArticleChemistryOpen2015

Design and Synthesis of Mixed Oligomers with Thiophenes, Dithienothiophene S,S-Dioxides, Thieno[3,4]pyrazines and 2,1,3-Benzothiadiazoles: Flipper Screening for Mechanosensitive Systems.

Quentin Verolet, Saeideh Soleimanpour, Kaori Fujisawa, Marta Dal Molin, Naomi Sakai, Stefan Matile

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemistryOpen, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Quentin VeroletDepartment of Organic Chemistry, University of Geneva Quai Ernest Ansermet 30, 1211, Geneva, Switzerland.
Saeideh SoleimanpourDepartment of Organic Chemistry, University of Geneva Quai Ernest Ansermet 30, 1211, Geneva, Switzerland.
Kaori FujisawaDepartment of Organic Chemistry, University of Geneva Quai Ernest Ansermet 30, 1211, Geneva, Switzerland.
Marta Dal MolinDepartment of Organic Chemistry, University of Geneva Quai Ernest Ansermet 30, 1211, Geneva, Switzerland.
Naomi SakaiDepartment of Organic Chemistry, University of Geneva Quai Ernest Ansermet 30, 1211, Geneva, Switzerland.
Stefan MatileDepartment of Organic Chemistry, University of Geneva Quai Ernest Ansermet 30, 1211, Geneva, Switzerland.
NCCR Chemical Biology - Visualisation and Control of Biological Processes Using Chemistry · CHUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monomers with large surface area and high quantum yield, that is fluorescent flippers, have been engineered into twisted push-pull oligomers to create membrane probes with high mechanosensitivity and long fluorescence lifetime. Here, the synthesis and characterization of thieno[3,4]pyrazines and 2,1,3-benzothiadiazoles are described in comparison with the original dithienothiophene S,S-dioxides. Dithienothiophene S,S-dioxide flippers are confirmed as the best reported so far, and poor results with single flipper probes support that two flippers are needed for the probe to really "swim", that is, for high mechanosensitivity.

Indexed as

fluorescent membrane probesmechanosensitivityoligomerspush–pull fluorophorestorsion anglestwisted fluorophores

Identifiers

PMID26246986
PMCPMC4522174
OpenAlexW2069213385

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.