Evidence map›Paper›PMID 26246802›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2015

Metabolic Consequences of LDHA inhibition by Epigallocatechin Gallate and Oxamate in MIA PaCa-2 Pancreatic Cancer Cells.

Qing-Yi Lu, Lifeng Zhang, Jennifer K Yee, Vay-Liang W Go, Wai-Nang Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolomics : Official journal of the Metabolomic Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.

  1. Natural products targeting glycolysis in cancer.Frontiers in pharmacology · 2022
    Pooled it
  2. Glucose metabolic phenotype of pancreatic cancer.World journal of gastroenterology · 2016
    Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Proteomics in pancreatic cancer.Biomarker research · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Qing-Yi LuDepartment of Medicine, University of California, Los Angeles, CA, USA.
Lifeng ZhangDepartment of Medicine, University of California, Los Angeles, CA, USA.
Jennifer K YeeDepartment of Pediatrics, Los Angeles Biomedical Research Institute, Torrance, CA, USA.
Vay-Liang W GoDepartment of Medicine, University of California, Los Angeles, CA, USA.
Wai-Nang LeeDepartment of Pediatrics, Los Angeles Biomedical Research Institute, Torrance, CA, USA.
University of California, Los Angeles · USThe Lundquist Institute · US

Funding

UCLA Center for Excellence in Pancreatic DiseasesP01AT003960 · NCCIH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GO, VAY LIANG W · 2007 to 2011
$5.6M
NCCIH NIH HHS P01 AT003960
6 · The paper itself

Abstract

Lactate dehydrogenase A (LDHA) is the enzyme that converts pyruvate to lactate and oxidizes the reduced form of nicotinamide adenine dinucleotide (NADH) to NAD

Indexed as

EGCGhuman pancreatic cancer MIA PaCa-2 cellsoxamatetracer based metabolomics

Identifiers

PMID26246802
PMCPMC4523095
OpenAlexW2067145600

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.