ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2016
Alcohol Dependence, Co-occurring Conditions and Attributable Burden.
Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Self-management with alcohol over lifespan: psychological mechanisms, neurobiological underpinnings, and risk assessment.Molecular psychiatry · 2023Pooled it
- Pooled it
- Association between alcohol consumption and impaired work performance (presenteeism): a systematic review.BMJ open · 2019Pooled it
- Cannabidiol and Alcohol Use Disorders: An Updated Review of Therapeutic Potential.Alcohol, clinical & experimental research · 2026Review
- Problematic Alcohol Use Among Adolescents in Germany: Representative Cross-Sectional Study.JMIR public health and surveillance · 2026Article
- Exploring the association between sweet liking and treatment response to naltrexone in patients with alcohol use disorder.The international journal of neuropsychopharmacology · 2026Article
- Enhancing Emotion Regulation and Overcoming Craving in Alcohol Dependence Syndrome Through Mindfulness-based Relapse Prevention.Indian journal of psychological medicine · 2025Article
- Liver Transplantation in Alcohol-Associated Liver Disease.Clinics in liver disease · 2025Review
- Enhancing opportunities to reduce escalation to substance use disorders through early engagement: a retrospective observational data linkage study of primary and secondary care in Wales.BMJ public health · 2025Article
- Akkermansia muciniphila Improves Depressive-Like Symptoms by Modulating the Level of 5-HT Neurotransmitters in the Gut and Brain of Mice.Molecular neurobiology · 2024Article
- The non-linear correlation between the severity of alcohol consumption and depressive symptoms in the Chinese Wa ethnic minority.Frontiers in public health · 2024Article
- Gut microbiota regulates chronic ethanol exposure-induced depressive-like behavior through hippocampal NLRP3-mediated neuroinflammation.Molecular psychiatry · 2023Article
- Association between Spinal Cord Injury and Alcohol Dependence: A Population-Based Retrospective Cohort Study.Journal of personalized medicine · 2022Article
- The Association of P300 Components With Clinical Characteristics and Efficacy of Pharmacotherapy in Alcohol Use Disorder.Frontiers in psychiatry · 2022Article
- How do individuals with alcohol problems use social and healthcare services in Finland? Comparison of service use patterns between two high-need patient groups.Nordisk alkohol- & narkotikatidskrift : NAT · 2021Article
- Young men's behavioral competencies and risk of alcohol use disorder in emerging adulthood: Early protective effects of parental education.Development and psychopathology · 2021Article
- Article
- Conversations about alcohol in healthcare - cross-sectional surveys in the Netherlands and Sweden.BMC public health · 2020Article
- Knowledge of Prevention Measures and Information About Coronavirus in Romanian Male Patients with Severe Mental Illness and Severe Alcohol Use Disorder.Neuropsychiatric disease and treatment · 2020Article
- Prevalence, Demographic, and Clinical Correlates of Comorbid Depressive Symptoms in Chinese Psychiatric Patients With Alcohol Dependence.Frontiers in psychiatry · 2020Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsAlcohol dependence is associated with high rates of co-occurring disorders which impact health-related quality of life (HRQoL) and add to the cost-of-illness. This study investigated the burden of alcohol dependence and associated co-occurring conditions on health and productivity.
methodsA cross-sectional survey was conducted in eight European countries. Physicians (Psychiatrists and General Practitioners) completed patient record forms, which included assessment of co-occurring conditions, and patients completed matching self-completion forms. Drinking risk level (DRL) was calculated and the relationship between DRL, co-occurring conditions, work productivity, hospitalisations and rehabilitation stays was explored.
resultsData were collected for 2979 alcohol-dependent patients (mean age 48.8 ± 13.6 years; 70% male). In total, 77% of patients suffered from moderate-to-severe co-occurring psychiatric and/or somatic conditions. High DRL was significantly associated with depression, greater work productivity losses, increased hospitalisations and rehabilitation stays. Co-occurring conditions were significantly associated with poorer HRQoL and decreased work productivity, with a statistical trend towards an increased frequency of rehabilitation stays.
conclusionsAlcohol-dependent patients manifest high rates of co-occurring psychiatric and somatic conditions, which are associated with impaired work productivity and HRQoL. The continued burden of illness observed in these already-diagnosed patients suggests an unmet need in both primary and secondary care.
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