ArticleDiabetes care2015
Environmentally Driven Increases in Type 2 Diabetes and Obesity in Pima Indians and Non-Pimas in Mexico Over a 15-Year Period: The Maycoba Project.
Article in Diabetes care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Population Heterogeneity of Diabetes in Indigenous Peoples of the Americas: A Systematic Scoping Review of the Existing Literature.Journal of personalized medicine · 2026Review
- Global landscape of kidney health across Indigenous populations.Nature reviews. Nephrology · 2026Review
- Dietary Inflammatory Index of Northern Mexican Indigenous Adults and Its Association with Obesity: Cross-Sectional Study.Nutrients · 2026Article
- The Endocrinological Basis for Polycystic Ovary Syndrome: An Evolutionary Perspective.Endocrinology · 2025Review
- Changes in energy expenditure and physical activity over 15 years of environmental changes: The Maycoba project.Obesity (Silver Spring, Md.) · 2024Article
- Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY.Nutrients · 2023Article
- Prevalence of overweight, obesity and central obesity and factors associated with BMI in indigenous yaqui people: a probabilistic cross-sectional survey.BMC public health · 2022Article
- Effectiveness of the Healthy Lifestyle Promotion Program for Yaquis with Obesity and Risk of Diabetes in the Short and Medium Term: A Translational Study.Journal of diabetes research · 2020Article
- Risk of developing pre-diabetes or diabetes over time in a cohort of Mexican health workers.PloS one · 2020Article
- Disparities in prediabetes and type 2 diabetes prevalence between indigenous and nonindigenous populations from Southeastern Mexico: The Comitan Study.Journal of clinical & translational endocrinology · 2019Article
- Analysis of type 2 diabetes and obesity genetic variants in Mexican Pima Indians: Marked allelic differentiation among Amerindians at HLA.Annals of human genetics · 2018Article
- Integrated analysis of the gene expression profile and DNA methylation profile of obese patients with type 2 diabetes.Molecular medicine reports · 2018Article
- The Nile Rat (Arvicanthis niloticus) as a Superior Carbohydrate-Sensitive Model for Type 2 Diabetes Mellitus (T2DM).Nutrients · 2018Review
- Prevalence of prediabetes and modifiable factors in an ethnic group of Mexico: the Comcáac Project.Public health nutrition · 2018Article
- Acute kidney injury in pregnancy and the role of underlying CKD: a point of view from México.Journal of nephrology · 2017Review
- Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes.BMC medicine · 2017Review
- Body composition and susceptibility to type 2 diabetes: an evolutionary perspective.European journal of clinical nutrition · 2017Review
- Insulin-sensitive adiposity is associated with a relatively lower risk of diabetes than insulin-resistant adiposity: the Bogalusa Heart Study.Endocrine · 2016Article
- Ethnic differences in prediabetes and diabetes in the Suriname Health Study.BMJ open diabetes research & care · 2016Article
- High-Risk Populations: The Pimas of Arizona and Mexico.Current obesity reports · 2015Review
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9 authors at 5 institutions in 2 countries.
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Abstract
objectiveThe global epidemics of type 2 diabetes and obesity have been attributed to the interaction between lifestyle changes and genetic predisposition to these diseases. We compared the prevalences of type 2 diabetes and obesity in Mexican Pima Indians, presumed to have a high genetic predisposition to these diseases, to those in their non-Pima neighbors, both of whom over a 15-year period experienced a transition from a traditional to a more modern lifestyle. RESEARCH DESIGN AND
methodsPrevalence of diabetes, impaired fasting glucose, impaired glucose tolerance, and obesity in Mexican Pimas (n = 359) and non-Pima Mexicans (n = 251) were determined in 2010 using methods identical to those used in 1995.
resultsDuring this 15-year period, age-adjusted diabetes prevalence was unchanged in Pima men (5.8% in 1995 vs. 6.1% in 2010) yet increased in non-Pima men from 0.0 to 8.6% (P < 0.05). Diabetes prevalence tended to increase in both Pima women (9.4 vs. 13.4%) and non-Pima women (4.8 vs. 9.5%). Age-adjusted prevalence of obesity increased significantly in all groups (6.6 vs. 15.7% in Pima men; 8.5 vs. 20.5% in non-Pima men; 18.9. vs 36.3% in Pima women; 29.5 vs. 42.9% in non-Pima women).
conclusionsType 2 diabetes prevalence increased between 1995 and 2010 in non-Pima men, and to a lesser degree in women of both groups, but it did not increase in Pima men. Prevalence of obesity increased among Pimas and non-Pimas of both sexes. These changes occurred concomitantly with an environmental transition from a traditional to a more modernized lifestyle.
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