SynthesisPlant physiology2015
Meta-Analysis of Arabidopsis KANADI1 Direct Target Genes Identifies a Basic Growth-Promoting Module Acting Upstream of Hormonal Signaling Pathways.
Synthesis in Plant physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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Who cites it
21 citing papers in PubMed, 31 citations in OpenAlex.
- Dexamethasone-inducible LhGR/pOp system: simple and flexible spatiotemporal control of gene expression.Planta · 2026Review
- Dynamic chromatin accessibility reveals BrKAN2 as a key regulator of Chinese cabbage leaf heading.Molecular horticulture · 2026Article
- Genome-Wide Identification of theInternational journal of molecular sciences · 2025Article
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- A fine-scale Arabidopsis chromatin landscape reveals chromatin conformation-associated transcriptional dynamics.Nature communications · 2024Article
- Differential CaKAN3-CaHSF8 associations underlie distinct immune and heat responses under high temperature and high humidity conditions.Nature communications · 2023Article
- KANADI promotes thallus differentiation and FR-induced gametangiophore formation in the liverwort Marchantia.The New phytologist · 2022Article
- Genome-Wide Identification and Characterization ofFrontiers in plant science · 2022Article
- Phytochrome regulates cellular response plasticity and the basic molecular machinery of leaf development.Plant physiology · 2021Article
- The Epigenetic Faces of ULTRAPETALA1.Frontiers in plant science · 2021Review
- An integrated analysis of cell-type specific gene expression reveals genes regulated by REVOLUTA and KANADI1 in the Arabidopsis shoot apical meristem.PLoS genetics · 2020Article
- Light affects tissue patterning of the hypocotyl in the shade-avoidance response.PLoS genetics · 2020Article
- Construction of the gene regulatory network identifies MYC as a transcriptional regulator of SWI/SNF complex.Scientific reports · 2020Article
- Systematic identification of genes associated with plant growth-defense tradeoffs under JA signaling in Arabidopsis.Planta · 2020Article
- Opposite physiological effects upon jasmonic acid and brassinosteroid treatment on laticifer proliferation and co-occurrence of differential expression of genes involved in vascular development in rubber tree.Physiology and molecular biology of plants : an international journal of functional plant biology · 2019Article
- A spatiotemporally regulated transcriptional complex underlies heteroblastic development of leaf hairs inThe EMBO journal · 2019Article
- The interaction between miR160 and miR165/166 in the control of leaf development and drought tolerance in Arabidopsis.Scientific reports · 2019Article
- Lateral Root Initiation in the Parental Root Meristem of Cucurbits: Old Players in a New Position.Frontiers in plant science · 2019Article
- Genome-wide analysis of RNAs associated with Populus euphratica Oliv. heterophyll morphogenesis.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An intricate network of antagonistically acting transcription factors mediates the formation of a flat leaf lamina of Arabidopsis (Arabidopsis thaliana) plants. In this context, members of the class III homeodomain leucine zipper (HD-ZIPIII) transcription factor family specify the adaxial domain (future upper side) of the leaf, while antagonistically acting KANADI transcription factors determine the abaxial domain (future lower side). Here, we used a messenger RNA sequencing approach to identify genes regulated by KANADI1 (KAN1) and subsequently performed a meta-analysis combining our data sets with published genome-wide data sets. Our analysis revealed that KAN1 acts upstream of several genes encoding auxin biosynthetic enzymes. When exposed to shade, we found three YUCCA genes, YUC2, YUC5, and YUC8, to be transcriptionally up-regulated, which correlates with an increase in the levels of free auxin. When ectopically expressed, KAN1 is able to transcriptionally repress these three YUC genes and thereby block shade-induced auxin biosynthesis. Consequently, KAN1 is able to strongly suppress shade-avoidance responses. Taken together, we hypothesize that HD-ZIPIII/KAN form the basis of a basic growth-promoting module. Hypocotyl extension in the shade and outgrowth of new leaves both involve auxin synthesis and signaling, which are under the direct control of HD-ZIPIII/KAN.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.