Observational studyInternational urology and nephrology2015
Post-renal transplantation anemia at 12 months: prevalence, risk factors, and impact on clinical outcomes.
Observational study in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of factors contributing to post-kidney transplant anemia and the effect of erythropoietin-stimulating agents.Systematic reviews · 2024Pooled it
- Smartphone-based point-of-care analyzer for rapid hemoglobin and potassium monitoring in end-stage renal disease and perioperative renal transplantation patients.Renal failure · 2026Article
- Ongoing and Novel Challenges in Kidney Transplantation: Therapeutic Approaches to Non-Immunological Risk Factors for Allograft Loss.Life (Basel, Switzerland) · 2026Review
- Anemia and iron deficiency in post-kidney transplantation: an unsolved challenge.Clinical kidney journal · 2025Review
- The Efficacy and Safety of Roxadustat for the Treatment of Posttransplantation Anemia: A Randomized Study.Kidney international reports · 2024Article
- Anemia after kidney transplantation.Pediatric nephrology (Berlin, Germany) · 2023Article
- Treatment Options for Anemia in Kidney Transplant Patients: A Review.Kidney medicine · 2023Review
- Postrenal transplant anemia and its effects on patients and graft outcomes: Seven years follow-up.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Article
- Risk factors and current state of therapy for anemia after kidney transplantation.Frontiers in medicine · 2023Review
- Roxadustat for treatment of anemia in a cancer patient with end-stage renal disease: A case report.World journal of clinical cases · 2022Article
- Prediction of kidney transplant outcome based on different DGF definitions in Chinese deceased donation.BMC nephrology · 2019Observational
- Development and future deployment of a 5 years allograft survival model for kidney transplantation.Nephrology (Carlton, Vic.) · 2019Article
- Post renal transplant anemia: severity, causes and their association with graft and patient survival.BMC nephrology · 2019Article
- Factors associated with anaemia in kidney transplant recipients in the first year after transplantation: a cross-sectional study.BMC nephrology · 2018Article
- Posttransplantation anemia in kidney transplant recipients: A retrospective cohort study.Medicine · 2017Observational
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11 authors.
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No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate any association between post-transplantation anemia (PTA) and clinical outcomes following living donor kidney transplantation.
methodsWe retrospectively evaluated 887 patients who received living donor kidney transplantations at our medical center between January 2006 and December 2012 to evaluate whether PTA, defined as serum hemoglobin (Hb) levels of <130 g/l in men and <120 g/l in women, at 12 months is associated with post-transplant outcomes, including graft function, death-censored graft survival, or patient survival.
resultsThe prevalence of PTA at 1, 3, 6, and 12 months was 84.3, 39.5, 26.2, and 21.6 %, respectively. Donor age [hazard ratio (HR), 1.03; 95 % confidence interval (CI) 1.01-1.05] and acute rejection (HR 2.13; 95 % CI 1.28-3.54) were found to be independent risk factors for PTA at 12 months. Recipient age (HR 0.98; 95 % CI 0.95-1.00), pre-transplantation Hb levels (HR 0.99; 95 % CI 0.98-1.00), and estimated glomerular filtration rates (eGFRs) at 12 months (HR 0.96; 95 % CI 0.94-0.97) were found to confer slight protection against PTA at 12 months. PTA at 12 months was associated with increased graft loss (HR 1.046; 95 % CI 1.045-1.046). For each increase in anemia degree, there was a 2.77-fold greater risk of graft loss (HR 2.77; 95 % CI 1.50-5.13). When stratified according to eGFR, PTA was found to be a predictor of graft loss in patients with an eGFR of <60 ml/min/1.73 m(2) (HR 4.57; 95 % CI 1.98-10.56) but not in patients with an eGFR of >60 ml/min/1.73 m(2) (HR 1.89; 95 % CI 0.13-27.78). PTA was not found to be a predictor of patient survival.
conclusionsAnemia is common after kidney transplantation, and its prevalence declines with time after transplantation. Presence of anemia at 12 months post-transplant was an independent predictor of graft loss, with higher risk of graft loss in patients with anemia and poorer kidney functions.
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