ArticleChinese journal of cancer2015
Incidence trends and age distribution of colorectal cancer by subsite in Guangzhou, 2000-2011.
Article in Chinese journal of cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- A systematic review of methods to estimate colorectal cancer incidence using population-based cancer registries.BMC medical research methodology · 2022Pooled it
- Statistical methods for measuring trends in colorectal cancer incidence in registries: A systematic review.Frontiers in oncology · 2022Pooled it
- Trends in the epidemiology of young-onset colorectal cancer: a worldwide systematic review.BMC cancer · 2020Pooled it
- Outcomes of preoperative chemoradiotherapy followed by surgery in patients with unresectable locally advanced sigmoid colon cancer.Chinese journal of cancer · 2016Trial
- Palliative primary tumor resection provides survival benefits for the patients with metastatic colorectal cancer and low circulating levels of dehydrogenase and carcinoembryonic antigen.Chinese journal of cancer · 2016Trial
- Colorectal cancer incidence and survival trends in Uganda: a population-based registry analysis (2000-20).International journal of epidemiology · 2026Article
- The Epidemiology of colorectal cancer in Guangzhou, China: A cross-sectional and age-period-cohort study.PLOS global public health · 2026Article
- RAS mutations and colorectal cancer metabolism: a metabolomic analysis of tissue samples.BMC cancer · 2025Article
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- Colorectal Cancer Incidence and Mortality Trends and Analysis of Risk Factors in China from 2005 to 2015.International journal of general medicine · 2021Article
- Different factors are associated with conventional adenoma and serrated colorectal neoplasia.Nagoya journal of medical science · 2020Article
- Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin.Journal of molecular cell biology · 2020Article
- Clinicopathological and Prognostic Characteristics of RAD51 in Colorectal Cancer.Medicina (Kaunas, Lithuania) · 2020Article
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- After laparoscopic liver resection for colorectal liver metastases, age does not influence morbi-mortality.Surgical endoscopy · 2019Article
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- Mass screening for colorectal cancer in a population of two million older adults in Guangzhou, China.Scientific reports · 2019Article
- Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications.Journal of the National Cancer Institute · 2019Article
- Analysis of population-based colorectal cancer screening in Guangzhou, 2011-2015.Cancer medicine · 2019Article
- Caveolin-1 Inhibits Proliferation, Migration, and Invasion of Human Colorectal Cancer Cells by Suppressing Phosphorylation of Epidermal Growth Factor Receptor.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
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7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionColorectal cancer (CRC) is the third most common cancer in China. The incidence of CRC has been increasing in recent years. The aim of this study was to explore the incidence trends and the age distribution of CRC by subsite in Guangzhou between 2000 and 2011.
methodsA total of 22,432 incident cases of CRC between 2000 and 2011 from Guangzhou Cancer Registry were identified. Crude incidence and age-standardized rates (ASRs), using the Segi's world standard population, were calculated for CRC and CRC subsites. The incidence trend was analyzed and the annual percentage change (APC) in incidence was calculated by using JoinPoint software.
resultsThe crude incidence increased significantly from 23.4/10(5) in 2000 to 37.4/10(5) in 2011 for males and from 20.9/10(5) to 30.5/10(5) for females. The ASRs of CRC incidence stabilized during the period of 2000-2011 for both males and females. The ages at the onset of CRC for both males and females during 2010-2011 were significantly higher compared with those during 2000-2002 (males: t = 1.95, P = 0.05; females: t = 6.03, P < 0.01). For males aged 50-64 years, the CRC incidence increased by 8.50% annually (P = 0.04) during 2000-2004 and by 1.68% annually (P = 0.03) during 2005-2011. For females aged 65 years and older, the CRC incidence increased by 5.77% annually (P = 0.03) during 2000-2004. There were no significant changes for the CRC incidences in males aged 49 and younger and 65 years and older and females aged 64 years and younger during 2000-2004, or for those in all females as well as males aged 49 years and younger and 65 years and older during 2005-2011. The percentage of colon cancer in all CRCs increased significantly for both males and females between the periods of 2000-2002 and 2010-2011. The ASRs of descending colon and sigmoid colon cancer incidences increased significantly for females during 2005-2011 (APC, 5.51% and 1.08%, respectively, both P < 0.05).
conclusionsThe crude incidence of CRC increased significantly between 2000 and 2011 because of the aging, whereas the ASRs kept stable. The percentage of colon cancer in all CRCs increased significantly. Further surveillance, research, and intervention are needed to identify the causes of these changes and to reduce the incidence and mortality of CRC.
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