Evidence map›Paper›PMID 26245367›Full record

ArticleEnvironmental research2015

Low correlation between household carbon monoxide and particulate matter concentrations from biomass-related pollution in three resource-poor settings.

Elizabeth M Klasen, Beatriz Wills, Neha Naithani, Robert H Gilman, James M Tielsch, Marilu Chiang, Subarna Khatry, Patrick N Breysse, Diana Menya, Cosmas Apaka and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Multinational modelling of PMScientific reports · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Household Air Pollution Is Associated with Altered Cardiac Function among Women in Kenya.American journal of respiratory and critical care medicine · 2018
    Article
  16. Article
  17. Article
  18. Article
  19. A review on recent progress in observations, sources, classification and regulations of PMEnvironmental science and pollution research international · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Elizabeth M KlasenDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, USA.
Beatriz WillsDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, USA.
Neha NaithaniDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, USA; Nepal Nutrition Intervention Project Sarlahi, Kathmandu, Nepal.
Robert H GilmanProgram in Global Disease Epidemiology and Control, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA.
James M TielschDepartment of Global Health, School of Public Health and Health Services, George Washington University, Washington DC, USA.
Marilu ChiangBiomedical Research Unit, A.B. PRISMA, Lima, Peru.
Subarna KhatryNepal Nutrition Intervention Project Sarlahi, Kathmandu, Nepal.
Patrick N BreysseDepartment of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA.
Diana MenyaSchool of Public Health, Moi University, Eldoret, Kenya; AMPATH (Academic Model Providing Access to Healthcare), Eldoret, Kenya.
Cosmas ApakaAMPATH (Academic Model Providing Access to Healthcare), Eldoret, Kenya.
E Jane CarterAMPATH (Academic Model Providing Access to Healthcare), Eldoret, Kenya; Division of Pulmonary Medicine, The Warren Alpert School of Medicine, Brown University, Providence, USA.
Charles B ShermanAMPATH (Academic Model Providing Access to Healthcare), Eldoret, Kenya; Division of Pulmonary Medicine, The Warren Alpert School of Medicine, Brown University, Providence, USA.
J Jaime MirandaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, USA; Program in Global Disease Epidemiology and Control, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, USA; CRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru. Electronic address: wcheckl1@jhmi.edu.
COCINAS Trial Working Group
Johns Hopkins University · USAMPATH · KEUniversidad Peruana Cayetano Heredia · PEBrown University · USGeorge Washington University · USJohns Hopkins Medicine · USMoi University · KEPrisma · PE

Funding

Medical Research Council MR/K007467/1NHLBI NIH HHS HHSN268200900033C
6 · The paper itself

Abstract

Household air pollution from the burning of biomass fuels is recognized as the third greatest contributor to the global burden of disease. Incomplete combustion of biomass fuels releases a complex mixture of carbon monoxide (CO), particulate matter (PM) and other toxins into the household environment. Some investigators have used indoor CO concentrations as a reliable surrogate of indoor PM concentrations; however, the assumption that indoor CO concentration is a reasonable proxy of indoor PM concentration has been a subject of controversy. We sought to describe the relationship between indoor PM2.5 and CO concentrations in 128 households across three resource-poor settings in Peru, Nepal, and Kenya. We simultaneously collected minute-to-minute PM2.5 and CO concentrations within a meter of the open-fire stove for approximately 24h using the EasyLog-USB-CO data logger (Lascar Electronics, Erie, PA) and the personal DataRAM-1000AN (Thermo Fisher Scientific Inc., Waltham, MA), respectively. We also collected information regarding household construction characteristics, and cooking practices of the primary cook. Average 24h indoor PM2.5 and CO concentrations ranged between 615 and 1440 μg/m(3), and between 9.1 and 35.1 ppm, respectively. Minute-to-minute indoor PM2.5 concentrations were in a safe range (<25 μg/m(3)) between 17% and 65% of the time, and exceeded 1000 μg/m(3) between 8% and 21% of the time, whereas indoor CO concentrations were in a safe range (<7 ppm) between 46% and 79% of the time and exceeded 50 ppm between 4%, and 20% of the time. Overall correlations between indoor PM2.5 and CO concentrations were low to moderate (Spearman ρ between 0.59 and 0.83). There was also poor agreement and evidence of proportional bias between observed indoor PM2.5 concentrations vs. those estimated based on indoor CO concentrations, with greater discordance at lower concentrations. Our analysis does not support the notion that indoor CO concentration is a surrogate marker for indoor PM2.5 concentration across all settings. Both are important markers of household air pollution with different health and environmental implications and should therefore be independently measured.

Indexed as

BiomassPovertyAir Pollution, IndoorCarbon MonoxideCookingEnergy-Generating ResourcesHousingKenyaNepalParticulate MatterPeruRural PopulationCarbon MonoxideParticulate MatterBiomass fuel smokeCarbon monoxideParticulate matterRndomized field trial

Identifiers

PMID26245367
PMCPMC4932836
OpenAlexW1555903253

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.