ArticlePloS one2015
An Overrepresentation of High Frequencies in the Mouse Inferior Colliculus Supports the Processing of Ultrasonic Vocalizations.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Hidden in plain sound: the scientific potential of house mouse squeaks.Biology letters · 2025Review
- Developmental encoding of natural sounds in the mouse auditory cortex.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Article
- Review
- Prestin-Mediated Frequency Selectivity Does not Cover Ultrahigh Frequencies in Mice.Neuroscience bulletin · 2022Article
- Hearing, touching, and multisensory integration during mate choice.Frontiers in neural circuits · 2022Review
- PIEZO2 mediates ultrasonic hearing via cochlear outer hair cells in mice.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Neuronal selectivity to complex vocalization features emerges in the superficial layers of primary auditory cortex.PLoS biology · 2021Article
- Hidden Hearing Loss Impacts the Neural Representation of Speech in Background Noise.Current biology : CB · 2020Article
- Cellular and Widefield Imaging of Sound Frequency Organization in Primary and Higher Order Fields of the Mouse Auditory Cortex.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Familiarity with social sounds alters c-Fos expression in auditory cortex and interacts with estradiol in locus coeruleus.Hearing research · 2018Article
- Go/No-Go task engagement enhances population representation of target stimuli in primary auditory cortex.Nature communications · 2018Article
- Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations.Nature communications · 2018Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Mice are of paramount importance in biomedical research and their vocalizations are a subject of interest for researchers across a wide range of health-related disciplines due to their increasingly important value as a phenotyping tool in models of neural, speech and language disorders. However, the mechanisms underlying the auditory processing of vocalizations in mice are not well understood. The mouse audiogram shows a peak in sensitivity at frequencies between 15-25 kHz, but weaker sensitivity for the higher ultrasonic frequencies at which they typically vocalize. To investigate the auditory processing of vocalizations in mice, we measured evoked potential, single-unit, and multi-unit responses to tones and vocalizations at three different stages along the auditory pathway: the auditory nerve and the cochlear nucleus in the periphery, and the inferior colliculus in the midbrain. Auditory brainstem response measurements suggested stronger responses in the midbrain relative to the periphery for frequencies higher than 32 kHz. This result was confirmed by single- and multi-unit recordings showing that high ultrasonic frequency tones and vocalizations elicited responses from only a small fraction of cells in the periphery, while a much larger fraction of cells responded in the inferior colliculus. These results suggest that the processing of communication calls in mice is supported by a specialization of the auditory system for high frequencies that emerges at central stations of the auditory pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.