Evidence map›Paper›PMID 26244975›Full record

Observational studyPloS one2015

Assessment of Cancer-Related Fatigue, Pain, and Quality of Life in Cancer Patients at Palliative Care Team Referral: A Multicenter Observational Study (JORTC PAL-09).

Satoru Iwase, Takashi Kawaguchi, Akihiro Tokoro, Kimito Yamada, Yoshiaki Kanai, Yoshinobu Matsuda, Yuko Kashiwaya, Kae Okuma, Shuji Inada, Keisuke Ariyoshi and 5 more

Open access · goldAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. The efficacy of music therapy to relieve pain, anxiety, and promote sleep quality, in patients with small cell lung cancer receiving platinum-based chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Trial
  3. Trial
  4. Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Comprehensive assessment of pain characteristics, quality of life, and pain management in cancer patients: a multi-center cross-sectional study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Article
  12. Article
  13. Review
  14. Observational
  15. Tryptophan and Kynurenine Pathway Metabolites and Psychoneurological Symptoms Among Breast Cancer Survivors.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2023
    Article
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Satoru IwaseDepartment of Palliative Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Takashi KawaguchiDepartment of Practical Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
Akihiro TokoroDepartment of Psychosomatic Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, Japan.
Kimito YamadaDepartment of Breast Surgery, Tokyo Medical University Hospital, Tokyo, Japan.
Yoshiaki KanaiDepartment of Palliative Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Yoshinobu MatsudaDepartment of Psychosomatic Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Sakai, Japan.
Yuko KashiwayaDepartment of Palliative Medicine, Tokyo Medical University Hospital, Tokyo, Japan.
Kae OkumaDepartment of Palliative Medicine, The University of Tokyo Hospital, Tokyo, Japan; Department of Radiology, The University of Tokyo Hospital, Tokyo, Japan.
Shuji InadaDepartment of Palliative Medicine, The University of Tokyo Hospital, Tokyo, Japan; Department of Psychosomatic Medicine, The University of Tokyo Hospital, Tokyo, Japan.
Keisuke AriyoshiDepartment of Palliative Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Japanese Organisation for Research and Treatment of Cancer (JORTC), NPO, Tokyo, Japan.
Tempei MiyajiJapanese Organisation for Research and Treatment of Cancer (JORTC), NPO, Tokyo, Japan; Department of Clinical Trial Data Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kanako AzumaDepartment of Pharmacy, Tokyo Medical University Hospital, Tokyo, Japan.
Hiroto IshikiDepartment of Palliative Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Japanese Organisation for Research and Treatment of Cancer (JORTC), NPO, Tokyo, Japan.
Sakae UnezakiDepartment of Practical Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
Takuhiro YamaguchiJapanese Organisation for Research and Treatment of Cancer (JORTC), NPO, Tokyo, Japan; Department of Clinical Trial Data Management, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Division of Biostatistics, Tohoku University Graduate School of Medicine, Sendai, Japan.
The University of Tokyo · JPTokyo Medical University Hospital · JPUniversity of Tokyo Hospital · JPNational Kinki Chuo Hospital for Chest Disease · JPTokyo University of Pharmacy and Life Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCancer-related fatigue greatly influences quality of life in cancer patients; however, no specific treatments have been established for cancer-related fatigue, and at present, no medication has been approved in Japan. Systematic research using patient-reported outcome to examine symptoms, particularly fatigue, has not been conducted in palliative care settings in Japan. The objective was to evaluate fatigue, pain, and quality of life in cancer patients at the point of intervention by palliative care teams. MATERIALS AND

methodsPatients who were referred to palliative care teams at three institutions and met the inclusion criteria were invited to complete the Brief Fatigue Inventory, Brief Pain Inventory, and European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-Palliative.

resultsOf 183 patients recruited, the majority (85.8%) were diagnosed with recurrence or metastasis. The largest group (42.6%) comprised lung cancer patients, of whom 67.2% had an Eastern Cooperative Oncology Group Performance Status of 0-1. The mean value for global health status/quality of life was 41.4, and the highest mean European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-Palliative symptom item score was for pain (51.0). The mean global fatigue score was 4.1, and 9.8%, 30.6%, 38.7%, and 20.8% of patients' fatigue severity was classified as none (score 0), mild (1-3), moderate (4-6), and severe (7-10), respectively. DISCUSSION: Cancer-related fatigue, considered to occur more frequently in cancer patients, was successfully assessed using patient-reported outcomes with the Brief Fatigue Inventory for the first time in Japan. Results suggested that fatigue is potentially as problematic as pain, which is the main reason for palliative care.

Indexed as

Quality of LifeAdultAgedAged, 80 and overFatigueFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasmsOutcome Assessment, Health CarePainPalliative CareReferral and ConsultationSurveys and Questionnaires

Identifiers

PMID26244975
PMCPMC4526465
OpenAlexW1885725815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.