Trial reportAnesthesiology2015
Influence of Ventilation Strategies and Anesthetic Techniques on Regional Cerebral Oximetry in the Beach Chair Position: A Prospective Interventional Study with a Randomized Comparison of Two Anesthetics.
Trial report in Anesthesiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 39 citations in OpenAlex.
- Different ventilation techniques and hemodynamic optimization to maintain regional cerebral oxygen saturation (rScOJournal of anesthesia · 2018Trial
- Cerebral oxygenation when ventilated or spontaneously breathing: a randomised control trial.Perioperative medicine (London, England) · 2025Article
- Carbon Dioxide, Blood Pressure, and Perioperative Stroke: A Retrospective Case-Control Study.Anesthesiology · 2022Article
- Cerebral Tissue Oxygen Saturation Correlates with Emergence from Propofol-Remifentanil Anesthesia: An Observational Cohort Study.Journal of clinical medicine · 2022Article
- Correlation between brain tissue oxygen tension and regional cerebral oximetry in uninjured human brain under conditions of changing ventilation strategy.Journal of clinical monitoring and computing · 2022Article
- Effects of different levels of controlled hypotension on regional cerebral oxygen saturation and postoperative cognitive function in patients undergoing total knee arthroplasty.Frontiers in medicine · 2022Article
- Effects of ultrasound-guided stellate ganglion block on the balance of the supply and demand of cerebral oxygen during permissive hypercapnia in patients undergoing shoulder arthroscopy in beach chair position.American journal of translational research · 2022Article
- Effect of Deliberate Hypotension on Regional Cerebral Oxygen Saturation During Functional Endoscopic Sinus Surgery: A Randomized Controlled Trial.Frontiers in surgery · 2021Article
- Adverse heart rate responses during beach-chair position for shoulder surgeries - A systematic review and meta-analysis of their incidence, interpretations and associations.Indian journal of anaesthesia · 2020Article
- [Cardiorespiratory effects of perioperative positioning techniques].Der Anaesthesist · 2019Review
- Cerebral Desaturation Events During Shoulder Arthroscopy in the Beach Chair Position.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2019Review
- Cerebral Oxygenation in the Sitting Position Is Not Compromised During Spontaneous or Positive-Pressure Ventilation.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2019Article
- Cerebrovascular Disease and Perioperative Neurologic Vulnerability: A Prospective Cohort Study.Frontiers in neurology · 2019Article
- Compression stockings reduce the incidence of hypotension but not that of cerebral desaturation events in the beach-chair position: a randomized controlled trial.Korean journal of anesthesiology · 2018Article
- Changes in cerebral oxygenation based on intraoperative ventilation strategy.Medical devices (Auckland, N.Z.) · 2018Article
- Effect of general anesthesia on serum β-amyloid protein and regional cerebral oxygen saturation of elderly patients after subtotal gastrectomy.Experimental and therapeutic medicine · 2016Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundBeach chair positioning during general anesthesia is associated with cerebral oxygen desaturation. Changes in cerebral oxygenation resulting from the interaction of inspired oxygen fraction (FIO2), end-tidal carbon dioxide (PETCO2), and anesthetic choice have not been fully evaluated in anesthetized patients in the beach chair position.
methodsThis is a prospective interventional within-group study of patients undergoing shoulder surgery in the beach chair position that incorporated a randomized comparison between two anesthetics. Fifty-six patients were randomized to receive desflurane or total intravenous anesthesia with propofol. Following induction of anesthesia and positioning, FIO2 and minute ventilation were sequentially adjusted for all patients. Regional cerebral oxygenation (rSO2) was the primary outcome and was recorded at each of five set points.
resultsWhile maintaining FIO2 at 0.3 and PETCO2 at 30 mmHg, there was a decrease in rSO2 from 68% (SD, 12) to 61% (SD, 12) (P < 0.001) following beach chair positioning. The combined interventions of increasing FIO2 to 1.0 and increasing PETCO2 to 45 mmHg resulted in a 14% point improvement in rSO2 to 75% (SD, 12) (P <0.001) for patients anesthetized in the beach chair position. There was no significant interaction effect of the anesthetic at the study intervention points.
conclusionsIncreasing FIO2 and PETCO2 resulted in a significant increase in rSO2 that overcomes desaturation in patients anesthetized in the beach chair position and that appears independent of anesthetic choice.
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